Medical Hypotheses
Volume 55, Issue 6 , Pages 480-484 , December 2000

Atherosclerotic plaque rupture: a fatigue process?

  • A.J. Bank

      Affiliations

    • Cardiovascular Division, Department of Medicine, University of Minnesota, Minneapolis, Minnesota, USA
    • ,
  • A. Versluis

      Affiliations

    • Minnesota Dental Research Center for Biomaterials and Biomechanics, University of Minnesota, Minneapolis, Minnesota, USA
    • ,
  • S.M. Dodge

      Affiliations

    • Cardiovascular Division, Department of Medicine, University of Minnesota, Minneapolis, Minnesota, USA
    • ,
  • W.H. Douglas

      Affiliations

    • Minnesota Dental Research Center for Biomaterials and Biomechanics, University of Minnesota, Minneapolis, Minnesota, USA

Received 12 November 1999 ,Accepted 16 February 2000.

References 

    REFERENCES
  1. Loree HM, Kamm RD, Atkinson CM, Lee RT. Turbulent pressure fluctuations on surface of model vascular stenoses. Am J Physiol. 1991;261:H644–H650
  2. Barger AC, Beeuwkes R, Lainey LL, Silverman KJ. Vasa vasorum and neovascularization of human coronary arteries: A possible role in the pathophysiology of atherosclerosis. N Engl J Med. 1991;88:8154–8158
  3. Leary T. Coronary spasm as a possible factor in producing sudden death. Am Heart J. 1934;10:338–344
  4. Richardson PD, Davies MJ, Born GVR. Influence of plaque configuration and stress distribution on fissuring of coronary atherosclerotic plaques. Lancet. 1989;2:941–944
  5. Callister WD. Materials science and engineering: An introduction. 4th ed. New York: John Wiley & Sons; 1997; p. 178–235
  6. Born GVR. Arterial thrombosis and its prevention. In:  Hayase S,  Murao S editor. Cardiology. Proceedings of the VIII World Congress of Cardiology; 1978 Sep 17–23; Tokyo, Japan. Amsterdam: Exerpta Medica; 1979;p. 81–91
  7. Falk E, Shah PK, Fuster V. Coronary plaque disruption. Circulation. 1995;92:657–671
  8. Farahmand, B. with Bockrath, G. Glassco, J. Fatigue and fracture mechanics of high risk parts: Application of LEFM & FMDM theory. New York, Chapman & Hall, 1997, 13, 102
  9. Rekhter MD, Hicks GW, Brammer DW. Animal model that mimics atherosclerotic plaque rupture. Circ Res. 1998;83:705–713
  10. Chenu P, Zakhia R, Marchandise B, Jamart J, Michel X, Schroeder E. Resistance of the atherosclerotic plaque during coronary angioplasty: A multivariate analysis of clinical and angiographic variables. Cath Cardiovasc Diagn. 1993;29:203–209
  11. Cheng GC, Loree HM, Kamm RD, Fishbein MC, Lee RT. Distribution of circumferential stress in ruptured and stable atherosclerotic lesions: A structural analysis with histopathological correlations. Circulation. 1993;87:1179–1187
  12. Falk E. Plaque rupture with severe pre-existing stenosis precipitating coronary thrombosis: Characteristics of coronary atherosclerotic plaques underlying fatal occlusive thrombi. Br Heart J. 1983;50:127–134
  13. Davies MJ, Richardson PD, Woolf N, Katz DR, Mann J. Risk of thrombosis in human atherosclerotic plaques: Role of extracellular lipid, macrophage, and smooth muscle cell content. Br Heart J. 1993;69:377–381
  14. Muller JE, Stone PH, Turi ZG. Circadian variation in the frequency of onset of acute myocardial infarction. N Engl J Med. 1985;313:1315–1322
  15. Meisel SR, Kutz I, Dayan KI. Effect of Iraqi missile war on incidence of acute myocardial infarction and sudden death in Israeli civilians. Lancet. 1991;338:660–661
  16. Leor J, Poole WK, Kloner RA. Sudden cardiac death triggered by an earthquake. N Engl J Med. 1996;334:413–419
  17. Leor J, Kloner RA. The Northridge earthquake as a trigger for acute myocardial infarction. Am J Cardiol. 1996;77:1230–1232
  18. Haskell WL. Cardiovascular complications during exercise training of cardiac patients. Circulation. 1978;57:920–924
  19. Rochmis P, Blackburn H. Exercise tests: A survey of procedures, safety, and litigation experience in approximately 170,000 tests. JAMA. 1971;217:1061–1066
  20. Johnstone MT, Mittleman M, Tofler G, Muller JE. The pathophysiology of the onset of morning cardiovascular events. Am J Hypertens. 1996;9:22S–28S
  21. Ridker PM, Manson JE, Buring JE, Muller JE, Hennekens CH. Circadian variation of acute myocardial infarction and the effect of low dose aspirin in a randomized trial of physicians. Circulation. 1990;82:897–902
  22. Dyer AR, Persky V, Stamler J. Heart rate as a prognostic factor for coronary disease and mortality: Findings in three Chicago epidemiologic studies. Am J Epidemiol. 1980;112:736–749
  23. Kannel WB, Kannel C, Paffenbarger RS, Cupples A. Heart rate and cardiovascular mortality: The Framingham Study. Am Heart J. 1987;113:1489–1494
  24. Gillman MW, Kannel WB, Belanger A, D’Agostino RB. Influence of heart rate on mortality among persons with hypertension: The Framingham Study. Am Heart J. 1993;125:1148–1154
  25. Aronow WS, Ahn C, Mercando AD, Epstein S. Association of average heart rate on 24-hour ambulatory electrocardiograms with incidence of new coronary events at 48-month follow-up in 1,311 patients (mean age 81 years) with heart disease and sinus rhythm. Am J Cardiol. 1996;78:1175–1176
  26. Fitzgerald JD. By what means might beta blockers prolong life after acute myocardial infarction?. Eur Heart J. 1987;8:945–951
  27. Kjekshus JK. Importance of heart rate in determi1ning beta-blocker efficacy in acute and long-term acute myocardial infarction intervention trials. Am J Cardiol. 1986;57:43F–49F
  28. Benetos A, Safar M, Rudnichi A. Pulse pressure: A predictor of long-term cardiovascular mortality in a French male population. Hypertension. 1997;30:1410–1415
  29. Madhavan S, Ooi WL, Cohen H, Alderman MH. Relation of pulse pressure and blood pressure reduction to the incidence of myocardial infarction. Hypertension. 1994;23:395–401
  30. Mitchell GF, Moye LA, Braunwald E. Sphygmomanometrically determined pulse pressure is a powerful independent predictor of recurrent events after myocardial infarction in patients with impaired left ventricular function. Circulation. 1997;96:4254–4260
  31. Little WC, Constantinescu M, Applegate RJ. Can coronary angiography predict the site of a subsequent myocardial infarction in patients with mild-to-moderate coronary artery disease?. Circulation. 1988;78:1157–1166
  32. Loree HM, Kamm RD, Stringfellow RG, Lee RT. Effects of fibrous cap thickness on peak circumferential stress in model atherosclerotic vessels. Circ Res. 1992;71:850–858
  33. Kannel WB. Blood pressure as a cardiovascular risk factor: Prevention and treatment. JAMA. 1996;275:1571–1576
  34. Collins R, Peto R, MacMahon S. Blood pressure, stroke, and coronary heart disease. Part 2, short-term reductions in blood pressure: overview of randomized drug trials in their epidemiological context. Lancet. 1990;335:827–838

PII: S0306-9877(00)91096-X

doi: 10.1054/mehy.2000.1096

Medical Hypotheses
Volume 55, Issue 6 , Pages 480-484 , December 2000

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