« Previous
Next »
Medical Hypotheses
Volume 55, Issue 6
, Pages 485-490
, December 2000
Lessons from pregnancy and parturition: uterine leiomyomas result from discordant differentiation and dedifferentiation responses in smooth muscle cells
References
- REFERENCES
-
.
Epidemiology of hysterectomy in the United States: demographic and reproductive factors in a nationally representative sample.
Journal of Women’s Health. 1997;6:309–316
- . Hysterectomy in the United States, 1988–1990. Obstet Gynecol. 1994;83:549–555
-
.
African Americans at higher risk than whites for uterine fibroids: ultrasound evidence.
Am J Epidemiol. 1998;147:358
- . Mitotic activity in uterine leiomyomas during the menstrual cycle. Am J Obstet Gynecol. 1989;160:637–641
- . Uterine leiomyomata: etiology, symptomatology, and management. Fertil Steril. 1981;36:433–445
- . Variation in the incidence of uterine leiomyoma among premenopausal women by age and race. Obstet Gynecol. 1997;90:967–973
- . Epidemiologic characteristics of women with uterine fibroids: a case-control study. Obstet Gynecol. 1988;72:853–857
- . Risk factors for uterine fibroids: reduced risk associated with oral contraceptives. BMJ. 1986;293:359–362
- . Body fat distribution and uterine leiomyomas. J Epidemiol. 1998;8:176–180
- . A conservative approach to the management of uterine leiomyoma. Pituitary desensitization by a luteinizing hormone releasing hormone analogue. Am J Obstet Gynecol. 1983;147:726–727
- . Predictors of uterine volume reduction in women with myomas treated with a gonadotropin-releasing hormone agonist. Fertil Steril. 1992;58:413–415
- . Chromosome analysis of 96 uterine leiomyomas. Cancer Genet Cytogenet. 1991;55:11–18
- . Analysis of genetic alterations in uterine leiomyomas and leiomyosarcomas by comparative genomic hybridization. Mol Carcinog. 1997;19:273–279
- . Loss of heterozygosity and reduced expression of the CUTLI gene in uterine leiomyomas. Oncogene. 1997;14:2355–2365
-
.
Two discrete regions of deletion at 7q in uterine leiomyomas.
Genes Chromosom Cancer. 1997;19:156–160
-
.
Molecular cytogenetic characterization of del(7q) in two uterine leiomyoma-derived cell lines.
Genes Chromosom Cancer. 1997;18:155–161
- . Many tumors and many genes: genetics of uterine leiomyomata. Am J Pathol. 1998;153:1015–1020
- . High-mobility-group chromosomal proteins: architectural components that facilitate chromatin function. Prog Nucleic Acid Res Mol Biol. 1996;54:35–100
- . HMGI(Y) expression in human uterine leiomyomata. Involvement of another high-mobility group architectural factor in a benign neoplasm [see comments]. Am J Pathol. 1997;150:911–918
- . Abnormal gene expression in uterine leiomyomas. J Soc Gynecol Investig. 1995;2:663–672
- . Modulation of gap junction transcript and protein expression during pregnancy in the rat. J Cell Biol. 1990;110:269–282
- . Gap junctions: their presence and necessity in myometrium during parturition. Science. 1977;198:958–960
- . Expression of connexin-43 in human myometrium and leiomyoma. Am J Obstet Gynecol. 1993;169:1266–1276
- . Steroid hormone regulation of rat myometrial gap junction formation: effects on cx43 levels and trafficking. Biol Reprod. 1995;52:547–560
-
.
The connexin43 gene is responsive to oestrogen.
Proc R Soc Lond B Biol Sci. 1994;255:125–132
- . Progestin represses human connexin43 gene expression similarly in primary cultures of myometrial and uterine leiomyoma cells. Biol Reprod. 1996;54:607–615
- . The effect of progestins on the mitotic activity of uterine fibromyomas. Int J Gynecol Pathol. 1985;4:89–96
- . Immunohistochemical analysis of oestrogen receptors, progesterone receptors and Ki-67 in leiomyoma and myometrium during the menstrual cycle and pregnancy. Virchows Arch A Pathol Anat Histopathol. 1991;419:309–315
- . Immunohistochemical analysis of human uterine estrogen and progesterone receptors throughout the menstrual cycle. J Clin Endocrinol Metab. 1988;67:334–340
- . Myometrial estradiol and progesterone receptor changes in preterm and term pregnancies. Obstet Gynecol. 1995;86:936–940
- . Progesterone receptor messenger ribonucleic acid and protein are overexpressed in human uterine leiomyomas. Am J Obstet Gynecol. 1993;169:78–85
- . Leiomyomas: steroid receptor content. Variation within normal menstrual cycles. Am J Obstet Gynecol. 1982;143:6–11
- . Comparative messenger ribonucleic acid analysis of immediate early genes and sex steroid receptors in human leiomyoma and healthy myometrium. J Clin Endocrinol Metab. 1997;82:2596–2600
- . Steroid receptor binding and messenger RNA expression in fibroids from untreated and gonadotrophin-releasing hormone agonist pretreated women. Clin Endocrinol (Oxf). 1994;40:537–544
- . Expression of progesterone receptor form A and B mRNAs in uterine leiomyoma. Tumor Biol. 1998;19:126–131
-
.
Immunoctyochemical analysis of oestrogen receptors and progesterone receptors in the human uterus throughout the menstrual cycle and after the menopause.
J Reprod Fert. 1992;94:363–371
-
.
Localization and expression of the human estrogen receptor beta gene in uterine leiomyomata.
Genes Chromosom Cancer. 1998;23:361–366
- . Estradiol and progesterone binding in uterine leiomyomata and in normal uterine tissues. Obstet Gynecol. 1980;55:20–24
-
.
Biology of uterine myomas and myometrium in vitro.
Semin Reprod Endocrinol. 1992;10:310–319
- . Sex steroid receptors in human myometrium and fibroids: changes during the menstrual cycle and gonadotropin-releasing hormone treatment. J Clin Endocrinol Metab. 1998;83:4092–4096
-
.
Regulation of myometrial composition, growth, and activity.
In:
Assali N editors. Biology of gestation I, the maternal organism. New York: Academic Press,; 1968;
- . Increased expression of stromelysin 3 mRNA in leiomyomas (uterine fibroids) compared with myometrium. J Soc Gynecol Investig. 1998;5:203–209
- . Extracellular matrix components in uterine leiomyoma and their alteration during the tumour growth. Mol Cell Biochem. 1998;189:145–152
-
.
Cultured human uterine smooth muscle cells are retinoid responsive.
PSEBM. 1997;215:59–65
- . Antiproliferative effect of retinoid compounds on kaposi’s sarcoma cells. J Clin Invest. 1994;93:1981–1986
-
.
Retinoid receptors in rat vaginal and uterine epithelia: changes with ovarian steroids.
Molec Cell Endocrin. 1997;132:101–108
-
.
Interaction of the peroxisome proliferator-activated receptor and retinoid x receptor.
Proc Natl Acad Sci USA. 1993;90:1440–1444
- . Convergence of 9-cis retinoic acid and peroxisome proliferator signaling pathways through heterodimer formation of their receptors. Nature. 1992;358:771–774
- . 15-Deoxy-delta 12, 14-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR gamma. Cell. 1995;83:803–812
-
.
Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptors alpha and gamma.
Proc Natl Acad Sci USA. 1997;94:4318–4323
- . Regulating adipogenesis. J Biol Chem. 1997;272:5367–5370
-
.
Expression of peroxisome proliferator-activated receptor (PPAR) in rat aortic smooth muscle cells.
Biochem Biophys Res Comm. 1998;247:353–356
- . Signaling cross-talk between peroxisome proliferator-activated receptor/retinoid X receptor and estrogen receptor through estrogen response elements. Mol Endocrinol. 1995;9:794–804
- . Retinoid X receptor and peroxisome proliferator-activated receptor activate an estrogen responsive gene independent of the estrogen receptor. Mol Cell Endocrinol. 1997;127:27–40
-
.
Estrogen-induced production of a peroxisome proliferator-activated receptor (PPAR) ligand in a PPARgamma-expressing tissue.
J Bio Chem. 1998;273:30131–30138
-
.
Spontaneous and radiation-induced renal tumors in the Eker rat model of dominantly inherited cancer.
Proc Natl Acad Sci USA. 1993;90:327–331
-
.
Predisposition to renal carcinoma in the Eker rat is determined by germ-line mutation of the tuberous sclerosis 2 (TSC2) gene.
Proc Natl Acad Sci USA. 1994;91:11413–11416
- . Tuberous sclerosis gene 2 product modulates transcription mediated by steriod hormone receptor family members. J Biol Chem. 1998;273:20535–20539
- . Suppression of cell proliferation and induction of apoptosis in uterine leiomyoma by gonadotropin-releasing hormone agonist (leuprolide acetate). J Clin Endocrinol Metab. 1998;83:1253–1255
- . Increased expression of Bcl-2 protein in human uterine leiomyoma and its up-regulation by progesterone. J Clin Endocrinol Metab. 1997;82:293–299
- . Regulation of apoptosis in uterine leiomyomata [published erratum appears in Endocrinology 1997 Sep; 138(9): 3786]. Endocrinology. 1997;138:3056–3064
-
.
Oestrogen and progesterone receptors in the involuting rat uterus.
Acta Endocrinol. 1982;100:450–454
- . Changes in expression of contractile FP and relaxatory EP2 receptors in pregnant rat myometrium during late gestation, at labor, and postpartum. Biol Reprod. 1998;59:878–883
-
.
Ultrastructure and Calcium Stores in the Myometrium.
In:
Carsten M, Miller J editor. Uterine Function: Molecular and Cellular Aspects. New York: Plenum Press; 1990;p. 1–34
- . Regulation of matrilysin in the rat uterus. Biochem Cell Biol. 1996;74:777–784
- . Collagenase 2 (MMP-8) expression in murine tissue-remodeling processes. Analysis of its potential role in postpartum involution of the uterus. J Biol Chem. 1998;273:23959–23968
- . Coordinate expression of matrix metalloproteinase family members in the uterus of normal, matrilysin-deficient, and stromelysin-1-deficient mice. Endocrinology. 1997;138:4902–4911
- . Collagenase production by smooth muscle: correlation of immunoreactive with functional enzyme in the myometrium. J Cell Physiol. 1986;129:111–123
PII: S0306-9877(00)91098-3
doi: 10.1054/mehy.2000.1098
© 2000 Harcourt Publishers Ltd. All rights reserved.
« Previous
Next »
Medical Hypotheses
Volume 55, Issue 6
, Pages 485-490
, December 2000
