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Medical Hypotheses
Volume 55, Issue 2
, Pages 93-98
, August 2000
Link between Helicobacter pylori infection and idiopathic parkinsonism
References
- REFERENCES
- . Symptomatology and medical treatment of Parkinson’s disease. Int J Neurol. 1961;2:61
-
.
The association of gastro-duodenal ulceration with Parkinson’s disease.
Med J Austr. 1965;52:842–843
- . Dopamine and gastroprotection. The Brain–Gut Axis. Dig Dis Sci. 1991;36:1670–1672
- . Gastric Helicobacter pylori infection as a cause of idiopathic Parkinson’s disease and non-arteric anterior optic ischemic neuropathy. Med Hypotheses. 1996;47:413–414
-
.
Unidentified curved bacilli on gastric epithelium in active chronic gastritis.
Lancet. 1983;i:1273–1275
- . Parkinsonism: siblings share Helicobacter pylori seropositivity and facets of syndrome. Acta Neurol Scand. 1999;99:26–35
-
.
Differential age-trend in Helicobacter pylori antibodies and its anthropometric implications, in idiopathic parkinsonism.
Gut. 1999;44:A67
- . Quantification of the cardinal signs of parkinsonism and of associated disability in spouses of sufferers. Age Ageing. 1993;22:20–26
- . Parkinson disease in twins: an etiologic study. JAMA. 1999;281:376–378
-
.
Helicobacter specific CD4+ T-cell clones from peripheral blood and gastric biopsies.
Infection Immunity. 1995;63:1102–1106
-
.
Enhanced T-helper-2 lymphocyte responses: immune mechanism of Helicobacter pylori infection.
Irish J Med Sci. 1996;165:37–39
- . T helper 1 effector cells specific for Helicobacter pylori in the gastric antrum of patients with peptic ulcer disease. J Immunol. 1997;158:962–967
-
.
Differential stimulation of interleukin-12 (IL-12) and IL-10 by live and killed Helicobacter pylori in vitro and association of IL-12 production with interferon gamma-producing T cells in human gastric mucosa.
Infection Immunity. 1997;65:4229–4235
- . Intestinal permeability and orocaecal transit time in elderly patients with Parkinson’s disease. Postgrad Med J. 1996;72:164–167
- . Detection of vacuolating toxin of Helicobacter pylori in human faeces. Lancet. 1993;341:1348
- . Gastrointestinal dysfunction in Parkinson’s disease: frequency and pathophysiology. Neurology. 1992;42:726–732
- . Dopaminergic defect of enteric nervous system in Parkinson’s disease patients with chronic constipation. Lancet. 1995;346:861–864
- . Parkinson’s disease and megacolon: concentric hyaline inclusions (Lewy bodies) in enteric ganglion cells. Neurology. 1987;37:1253–1255
- . Reactive microglia are positive for HLA-DR in the substantia nigra of Parkinson’s and Alzheimer’s disease brains. Neurology. 1988;38:1285–1289
- . Amyotrophic lateral sclerosis, Parkinson’s disease and Alzheimer’s disease: phylogenetic disorders of the human neocortex sharing many characteristics. Can J Neurol Sci. 1992;19:117–123
- . Immunocytochemical analysis of tumour necrosis factor and its receptors in Parkinson’s disease. Neurosci Lett. 1994;172:151–154
- . Interleukin-1-beta, interleukin-6, epidermal growth-factor-alpha and transforming growth-factor-alpha are elevated in the brain from parkinsonian patients. Neurosci Lett. 1994;180:147–150
- . Interleukin (IL)-1 beta, IL-2, IL-4, IL-6 and transforming growth factor-alpha levels are elevated in ventricular cerebrospinal fluid in juvenile parkinsonism and Parkinson’s disease. Neurosci Lett. 1996;211:13–16
- . Parkinson’s disease and immunological abnormalities: increase of HLA-DR expression on monocytes in cerebrospinal fluid and of CD45RO+T cells in peripheral blood. Acta Neurol Scand. 1994;90:160–166
- . γδ+ T cells are increased in patients with Parkinson’s disease. J Neurol Sci. 1994;121:39–45
- . A correlation study between serum adenosine-deaminase activities and peripheral lymphocyte subsets in Parkinson’s disease. J Neurol Sci. 1995;132:170–173
- . Topographic study of Helicobacter pylori and HLA-DR expression on gastric mucosa. J Gastroenterol. 1995;30:149–155
- . An increased number of gamma/delta T-cells and gastric epithelial cell expression of the groEL stress-protein homologue in Helicobacter pylori -associated chronic gastritis of the antrum. Am J Gastroenterol. 1991;86:976
-
.
Autoimmunity in Parkinson’s disease.
In:
Hassler RG, Christ JF editor. Parkinson-specific Motor and Mental Disorders. Role of the Pallidum: Pathophysiological, Biochemical and Therapeutic Aspects.. New York: Raven Press; 1984;p. 307–313
-
.
Investigations on auto-antibodies in Alzheimer’s and Parkinson’s diseases, using defined neuronal cultures.
J Neural Transm. 1990;29:195–206
- . Humoral response to hsp 65 and hsp 70 in cerebrospinal fluid in Parkinson’s disease. J Neurol Sci. 1996;139:66–70
- . Experimental destruction of substantia nigra initiated by Parkinson disease immunoglobulins. Arch Neurol. 1998;55:1075–1080
-
.
Parkinson’s disease, Alzheimer’s disease and motorneurone disease: abiotrophic interaction between ageing and environment?.
Lancet. 1986;ii:1067–1070
- . When does Parkinson’s disease begin?. Neurology. 1992;42:27–31
-
.
The neurology of old age.
Lancet. 1931;i:1221–1230
- . Aging and the extrapyramidal system. J Am Geriatr Soc. 1973;21:145–149
- . Hypothesis: age-associated changes in gait represent, in part, a tendency towards parkinsonism. Age Ageing. 1992;21:221–225
- . Objective measurement of activation of rigidity: diagnostic, pathogenetic and therapeutic implications in parkinsonism. Br J Clin Pharmacol. 1996;41:557–564
- . Extrapyramidal signs in cognitively intact elderly people. Age Ageing. 1998;27:557–560
- . Association of circulating TNF-α and IL-6 with ageing and parkinsonism. Acta Neurol Scand. 1999;100:34–41
- . HLA-DR expression on CD8 lymphocytes from gastric mucosa in urease-positive and urease-negative gastritis. FEMS Immunol Med Microbiol. 1995;10:295–299
- . Cortisol is higher in parkinsonism and associated with gait deficit. Acta Neurol Scand. 1998;97:77–85
-
.
Perceptions, emotions and immunity: an integrated homeostatic network.
Q J Med. 1995;88:283–294
- . Cytokines and the nervous system II: actions and mechanisms of action. Trends Neurosci. 1995;18:130–136
-
Male, D. Cooke, C. Owen, M. Trowsdale, J. Champion, B. Advanced Immunology. London, Mosby, 1996
- . The role if interleukin-6 in certain age-related diseases. Drugs Aging. 1994;5:358–365
- . Hypothesis: the bradyphrenia of parkinsonism is a nosological entity. Acta Neurol Scand. 1993;87:255–261
- . Assessment of the bradyphrenia of parkinsonism: a novel use of delayed auditory feedback. Acta Neurol Scand. 1993;87:262–267
- . Relationship of motor symptoms to intellectual deficits in Parkinson’s disease. Neurology. 1982;32:133–137
-
.
Age-related changes of human serum antibodies to dietary and colonic bacterial antigens measured by enzyme-linked immunosorbent assay.
Acta Path Microbiol Immunol Scand – Section C. 1985;93:65–70
-
.
Stimulatory effects of Helicobacter pylori on human peripheral mononuclear cells of H. pylori infected patients and healthy blood donors.
Zentrabl Bakteriol. 1993;280:166–176
- . Specific neutrophil hyporesponsiveness in chronic Helicobacter pylori infection. J Infect Dis. 1996;174:544–551
-
.
The stimulation and inhibition of T cell proliferation by Helicobacter pylori components.
J Physiol Pharmcol. 1996;47:195–202
-
.
The proliferation of human T lymphocytes stimulated by Helicobacter pylori antigens.
Immunobiol. 1996;195:199–208
- . Helicobacter pylori infection induces antibodies cross-reacting with human gastric mucosa. Gastroenterology. 1991;101:437–445
- . Molecular mimicry between Helicobacter pylori and the host. Trends Microbiol. 1997;5:70–73
-
.
Who gets false-negative H. pylori (HP) ELISA results?.
Gut. 1994;35:S51
-
.
Is Helicobacter pylori antigen responsible for changes in circulating immunoglobulin associated with ageing?.
Br J Pharmacol. 1999;127:80P
-
.
Evidence for autoimmunity triggered by Helicobacter pylori in idiopathic parkinsonism.
Br J Pharmacol. 2000;49:506P
-
.
Heat shock proteins of Helicobacter pylori..
Aliment Pharmacol Ther. 1996;10:51–56
- . Multiple sclerosis: immune system molecule expression in the central nervous system. J Neuropathol Exp Neurol. 1994;53:328–337
- . Cytokine production by helper T cell populations from the synovial fluid and blood in patients with rheumatoid arthritis. J Rheumatol. 1993;20:1647–1653
- . Circulating antibodies to the 60-kD heat shock protein (hsp) family in patients with Helicobacter pylori infection. Clin Exp Immunol. 1998;112:490–494
-
Parkinson, J. Essay on the Shaking Palsy. London, Sherwood, Neely & Jones, 1817
-
.
Rapid elimination of Helicobacter pylori and reduction of histocompatibility leukocyte antigen-DR expression 12
h after a single dose of omeprazole, amoxycillin and metronidazole triple therapy.
J Gastroenterol Hepatol. 1999;14:322–327
PII: S0306-9877(00)91110-1
doi: 10.1054/mehy.2000.1110
© 2000 Harcourt Publishers Ltd. All rights reserved.
Next »
Medical Hypotheses
Volume 55, Issue 2
, Pages 93-98
, August 2000
