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Medical Hypotheses
Volume 57, Issue 2
, Pages 180-182
, August 2001
Effects of tetrahydrobiopterin on ataxia in Machado-Joseph disease may be based upon the theory of ‘cerebellar long-term depression’
References
- REFERENCES
- . Joseph disease in a non-Portuguese family. Neurology. 1983;33:74–80
- . Clinical and molecular features of spinocerebellar ataxia type 6. Neurology. 1997;49:1243–1246
- . Incidence of dominant spinocerebellar and Friedreich triplet repeats among 361 ataxia families. Neurology. 1998;51:1666–1671
- . Prevalence of triplet repeat expansion in ataxia patients from Hokkaido, the nothernmost island of Japan. J Neurol Sci. 2000;175:45–51
-
.
The gene for Machado-Joseph disease maps to human chromosome 14q.
Nature Genet. 1993;4:300–304
-
.
CAG expansions in a novel gene from Machado-Joseph disease at chromosome 14q32.1.
Nature Genet. 1994;8:221–228
- . Sulfamethoxazole-trimethoprim double-blind, placebo-controlled, crossover trial in Machado-Joseph disease: sulfamethoxazole-trimethoprim increases cerebrospinal fluid level of biopterin. J Neural Transm (Gen Sect). 1995;102:159–172
- . Tetrahydro-biopterin double-blind, crossover trial in Machado-Joseph disease. J Neurol Sci. 1996;136:71–72
- . Climbing fibre induced depression of both mossy fibre responsiveness and glutamate sensitivity of cerebellar Purkinje cells. J Physiol. 1982;324:113–134
- . Long-term depression. Annu Rev Neurosci. 1989;12:85–102
- . Cerebellar long-term depression (Letter). Trends Neurosci. 1996;19:11–12
-
.
Nitric oxide plays a key role in adaptive control of locomotion in cat.
Proc Natl Acad Sci USA. 1996;93:13292–13297
- . Expression of a protein kinase C inhibitor in Purkinje cells blocks cerebellar LTD and adaptation of the vestibulo-ocular reflex. Neuron. 1998;20:495–508
- . Endogenous nitric oxide release required for long-term synaptic depression in the cerebellum. Nature. 1991;349:326–328
- . Long-term depression requires nitric oxide and guanosine 3′:5′ cyclic monophosphate production in rat cerebellar Purkinje cells. Eur J Neurosci. 1993;5:1079–1082
- . Long-term depression in rat cerebellum requires both NO synthase and NO-sensitive guanylyl cyclase. Eur J Neurosci. 1996;8:2209–2212
- . Stimulation of human nitric oxide synthase by tetrahydrobiopterin and selective binding of the cofactor. FEBS Lett. 1992;305:160–162
- . (6R)-5,6,7,8-tetrahydro-L-biopterin modulates nitric oxide-associated soluble guanylate cyclase activity in the rat cerebellum. Arch Biochem Biophys. 1992;298:726–730
- . Acute effects of tetrahydrobiopterin on the dynamic characteristics and adaptability of vestibulo-ocular reflex in normal and flocculus lesioned rabbits. Neurosci Lett. 1997;231:41–44
PII: S0306-9877(01)91293-9
doi: 10.1054/mehy.2001.1293
© 2001 Harcourt Publishers Ltd. All rights reserved.
« Previous
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Medical Hypotheses
Volume 57, Issue 2
, Pages 180-182
, August 2001
