Medical Hypotheses
Volume 57, Issue 2 , Pages 183-185, August 2001

Can glucose-insulin-potassium regimen suppress inflammatory bowel disease?

EFA Sciences LLC, Suite #266, 1420 Providence Highway, Norwood, MA, 02062, USA

Received 28 September 2000; accepted 17 January 2001.

Abstract 

Insulin seems to have the ability to suppress the production of tumor necrosis factor- α and superoxide anion, enhance the synthesis of nitric oxide and inhibit the expression of intercellular adhesion molecule-1 (ICAM-1) through stimulation of nitric oxide. This suggests that insulin can behave as an anti-inflammatory molecule. In view of this, it is suggested that insulin in combination with glucose and potassium may be of benefit in the management of inflammatory bowel disease.

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PII: S0306-9877(01)91334-9

doi:10.1054/mehy.2001.1334

Medical Hypotheses
Volume 57, Issue 2 , Pages 183-185, August 2001

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