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Medical Hypotheses
Volume 58, Issue 1
, Pages 47-60
, January 2002
The central role of magnesium deficiency in Tourette's syndrome: causal relationships between magnesium deficiency, altered biochemical pathways and symptoms relating to Tourette's syndrome and several reported comorbid conditions
References
- . Tourette's disorder and related problems: a review and update. Harv Rev Psychiatry. 1994;2:121–132
-
.
[Tics and Gilles de la Tourette syndrome].
Arq Neuropsyquiatr. 1995;53:141–146
-
.
Tourette syndrome: phenomenology, pathophysiology, genetics, epidemiology and treatment.
Curr Neurol. 1992;13:8
-
.
Tourette's Syndrome. Part I: definition and diagnosis and Tourette's syndrome. Part II: Contemporary approaches to assessment and treatment.
Arch Psychiat Nurs. 1993;7:203–216
- . Gilles de la Tourette Syndrome. Can J Neurol Sci. 1994;21:48–52
- . Differential effects of transdermal nicotine on microstructured analyses of tics in Tourette's syndrome: an open study. Psychol Med. 1997;27:483–487
- . Severe motor tics causing cervical myelopathy in Tourette's syndrome. Mov Disord. 1996;11:563–566
-
.
Tourette syndrome: clinical and psychological aspects of 250 cases.
Am J Hum Genet. 1985;37:718
- . Sensory tics in Tourette's syndrome. Neurology. 1989;39:731–734
- . Tourette's syndrome in patients referred for allergy evaluation. Ann Allergy Asthma Immunol. 1997;79:347–349
- . Sensory experience as a trigger in Gilles de la Tourette's syndrome. J Behav Ther Exp Psychiatry. 1983;14:197–201
- . Sensory phenomena in Tourette's syndrome. Adv Neurol. 1995;65:273–280
- . Sensory phenomena associated with Gilles de la Tourette's syndrome. J Clin Psychiatry. 1992;53:319–323
- . The biochemistry of Tourette's syndrome. Metabolic Brain Disease. 1995;10:107–124
- . [Gilles de la Tourette syndrome]. [Review]. Ugeskrift for Laeger. 1993;155:3759–3763
- . Multiple tic syndrome (Gilles de la Tourette's syndrome). J Nerv Ment Dis. 1974;15:282–292
-
.
Neuropsychiatric disorders of childhood: Tourette's syndrome as a model.
Acta Paediatr Suppl. 1997;22:106–111
-
Castellanos, F. X. Giedd, J. N. Elia, J. et al., Controlled stimulant treatment of ADHD and comorbid Tourette's syndrome: effects of stimulant and dose, J Am Acad Child Adolesc Psychiatry, 36, 589, 596
-
.
Considerations of natural history and pathophysiology in the psychopharmacology of Tourette's syndrome.
J Clin Psychiatry. 1996;57:24–34
- . Tics and dyskinesias associated with stimulant treatment in attention-deficit hyperactivity disorder. Arch Pediatr Adolesc Med. 1994;148:859–861
- . Gilles de la Tourette's syndrome: tics and central nervous system stimulants in twins and nontwins. Neurology. 1986;36:232–237
- . Stimulant medications precipitate Tourette's syndrome. JAMA. 1982;247:1168–1169
- . Gilles de la Tourette's syndrome. Familial occurrence and precipitation by methylphenidate therapy. Arch Neurol. 1977;34:630–632
- . [Exacerbation of tics by prednisolone]. [Article in German]. Nervenarzt. 1998;69:1111–1114
- . Significant linkage for Tourette syndrome in a large French Canadian family. Am J Hum Genet. 2000;67:1008–1013
- . Significant linkage for Tourette syndrome in a large French Canadian family. Am J Hum Genet. 2000;67:1008–1013
- . Identification of genetic markers associated with Gilles de la Tourette syndrome in an Afrikaner population. Am J Hum Genet. 1998;63:839–846
- . Identification of genetic markers associated with Gilles de la Tourette syndrome in an Afrikaner population. Am J Hum Genet. 1998;63:839–846
- . Tourette's disorder and related problems: a review and update. Harv Rev Psychiatry. 1994;2:121–132
- . The early course of the Tourette's syndrome clinical spectrum. Neurology. 1993;43:1712–1715
- . Tourette syndrome and autistic disorder: a significant relationship. Am J Med Genet. 1991;39:173–179
- . Fluvoxamine treatment of coincident autistic disorder and obsessive-compulsive disorder: a case report. J Autism Dev Disord. 1990;20:537–543
- . Attention-deficit hyperactivity in adults. Postgrad Med. 1996;100:207–211, 215–218
- . Role of genetic factors in human sexual behavior based on studies of Tourette syndrome and ADHD probands and their relatives. Am J Med Genet. 1994;54:227–241
- . Tourette syndrome. Coprolalia and other coprophenomena. Neurol Clin. 1997;15:299–308
- . Obsessive-compulsive disorder with and without tics in an epidemiological sample of adolescents. Am J Psychiatry. 1997;154:274–276
- . Stimulus induced behaviours in Tourette's syndrome. J Neurol Neurosurg Psychiatry. 1994;57:853–855
- . Sensory phenomena associated with Gilles de la Tourette's syndrome. J Clin Psychiatry. 1992;53:319–323
- . A controlled study of Tourette syndrome. I. Attention-deficit disorder, learning disorders, and school problems. Am J Hum Genet. 1987;41:701–741
- . Examining the evidence foranxiety-related cognitive biases in obsessive-compulsive disorder. J Anxiety Disord. 1998;12:579–598
- . Enhanced stress responsitivity of Tourette syndrome patients undergoing lumbar puncture. Biological Psychiatry. 1994;36:35–43
- . Tourette's syndrome and psychopathology in a child psychiatry setting. J Am Acad Child Adolesc Psychiatry. 1997;36:1618–1624
- . Rage attacks in children and adolescents with Tourette's disorders: a pilot study. J Clin Psychiatry. 1998;59:576–580
- . Paroxetine treatment of episodic rages associated with Tourette's disorder. J Clin Psychiatry. 1998;59:581–584
- . Self-injurious behaviour in retarded children: clinical phenomena and biological mechanisms. Acta Paedopsychiatr. 1993;56:105–111
-
.
Asthma, allergies and TS.
Tourette Syndrome Association Inc. Newsletter. 1996;24:3,13
- . Association of allergy with Tourette's syndrome. J Formos Med Assoc. 1999;98:492–495
- . Attention deficit disorder and allergy: a neurochemical model of the relation between the illnesses. Psychol Bull. 1989;106:434–446
- . Foods and additives are common causes of the attention deficit hyperactive disorder in children. Ann Allergy. 1994;72:462–468
-
.
Neuropharmacological evaluation of movement disorders that are adverse reactions to specific foods.
Int J Neurosci. 1994;7:61–69
- . Allergy and Tourette's syndrome. Annals of Allergy. 1985;55:119–121
- . Tourette's syndrome and migraine. Arch Neurol. 1984;41:871–872
- . Periodic limb movements during sleep are a frequent finding in patients with Gilles de la Tourette's syndrome. J Neurol. 1997;244:521–526
-
.
Further studies on periodic limb movement disorder and restless legs syndrome in children with attention deficit hyperactivity disorder.
Movement Disorders. 1999;14:1000–1007
- . Case study: a new infection-triggered, autoimmune subtype of pediatric OCD and Tourette's syndrome. J Am Acad Child Adolesc Psychiatry. 1995;34:307–311
- . Identification of children with pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections by a marker associated with rheumatic fever. Am J Psychiatry. 1997;154:110–112
-
Comings, D. E. Genetic factors in substance abuse based on studies of Tourette Syndrome and ADHD probands and relatives. II. Alcohol abuse, Drug Alcohol Depend, 1994, 35, 17, 24
- . New experimental and clinical data on the relationship between magnesium and sport. Magnes Res. 1990;3:93–102
- . Neurotic, neuromuscular and autonomic nervous form of magnesium imbalance. Magnes Res. 1997;10:169–195
- . Magnesium, stress and neuropsychiatric disorders. Magnes Trace Elem. 1991;10:287–301
- . Central nervous system magnesium deficiency. Arch Intern Med. 1991;151:593–596
- . Physiological correlates of abnormal behaviors in magnesium-deficient rats. Epilepsy Research. 1993;15:81–89
-
Holvey, D. N. The Merck Manual, Rahway, NJ, Merck Sharp & Dohme Research Laboratories, 1972, 1091
-
.
[Bruxism and magnesium, my Clinical experiences since 1980]. [Article in French].
Rev Stomatol Chir Maxillofac. 1990;91:127
- . Interrelationship of magnesium and estrogen in cardiovascular and bone disorders, eclampsia, migraine and premenstrual syndrome. J Am Coll Nutr. 1993;12:442–458
- . Migraine treatment by oral magnesium intake and correction of the irritation of buccofacial and cervical muscles as a side effect of mandibular imbalance. Magnes Res. 1994;7:123–127
-
.
Bruxism and magnesium. Literature review and case reports.
Proc Finn Dent Soc. 1974;70:217–224
-
.
[Bruxism and magnesium, my clinical experiences since 1980]. [Article in French].
Rev Stomatol Chir Maxillofac. 1990;91:127
- . Clinical, EEG, electromyographic and polysomnographic studies in restless legs syndrome caused by magnesium deficiency. Rom J Neurol Psychiatry. 1993;31:55–61
- . Magnesium therapy for periodic leg movements-related insomnia and restless legs syndrome: an open pilot study. Sleep. 1998;21:501–505
- . Intracellular (Polymorphonuclear) magnesium content in patients with bronchial asthma between attacks. J R Soc Med. 1995;88:441–445
- . Magnesium, stress and neuropsychiatric disorders. Magnes Trace Elem. 1991;10:287–301
- . Physiological correlates of abnormal behaviours in magnesium-deficient rats. Epilepsy Research. 1993;15:81–89
-
.
Tietz Textbook of Clinical Chemistry. Philadelphia: W. B. Saunders Company; 1994;
p. 1953–1954
- . [Various neurophysiological aspects of examination of children with Gilles de la Tourette's syndrome]. [Article in Russian]. Zh Nevropatol Psikhiatr Im S S Korsakova. 1991;91:57–59
- . Dental treatment of patients with Gilles de la Tourette's syndrome. Oral Surg Oral Med Oral Pathol. 1992;73:299–303
- . Tourette's syndrome associated with restless legs syndrome and akathisia in a family. Acta Neurol Scand. 1994;89:429–432
-
.
[Gilles de la Tourette syndrome associated with epileptiform discharges; report of three cases]. [Chinese].
Chung Hua Min Kuo Hsiao Erh Ko I Hsueh Hui Tsa Chih. 1989;30:61–65
- . Role of magnesium in the pathogenesis and treatment of migraines. Clin Neurosci. 1998;5:24–27
- . Aromatic amines (serotonin and histamine) and magnesium deficiency in the rat. Int J Vitam Nutr Res. 1980;50:185–192
- . Magnesium and immune function: an overview. [Review]. Magnesium. 1988;7:290–299
- . Changes in histamine and white blood cells in the blood, spleen and thymus of magnesium deficient rat. Reprod Nutr Dev. 1981;21:591–600
-
.
Tietz Textbook of Clinical Chemistry. Philadelphia: W. B. Saunders Company; 1994;
p. 1953–1954
- . Recent data on mitral valve prolapse and magnesium deficit. Magnes Res. 1988;1:203–211
- . Assessment of magnesium levels in children with attention deficit hyperactivity disorder (ADHD). Magnes Res. 1997;10:143–148
- . [The effect of deficiency of selected bioelements on hyperactivity in children with certain specified mental disorders]. [Article in Polish]. Ann Acad Med Stetin. 1998;44:297–314
- . The effects of magnesium physiological supplementation on hyperactivity in children with attention deficit disorder (ADHD). Positive response to magnesium oral loading test. Magnes Res. 1997;10:149–156
- . Hereditary isolated renal magnesium loss maps to chromosome 11q23. Am J Hum Genet. 1999;64:180–188
-
.
Neurogenic peptides and the cardiomyopathy of magnesium-deficiency: effects of substance P-receptor inhibition.
Molecular & Cellular Biochemistry. 1994;130:103–109
- . Immunoregulation by neuropeptides in magnesium deficiency: ex vivo effect of enhanced substance P production on circulating T lymphocytes from magnesium-deficient mice. Magnes Res. 1996;9:3–11
- . Enhanced NO production during Mg deficiency and its role in mediating red blood cell glutathione loss. Am J Physiol. 1996;271:C385–C390
- . On kynureninase activity. Adv Exp Med Biol. 1991;294:523–526
- . Increased plasma kynurenine and its relationship to neopterin and tryptophan In Tourette's syndrome. Psychological Medicine. 1996;26:857–862
-
.
In:
Schwarcz R, Young SN, Brown RR editor.
Kynurenine and Serotonin Pathways. New York: Plenum Press; 1991;p. 663–668
- . Caffeine-induced anxiety and increase of kynurenine concentration in plasma of healthy subjects: a pilot study. Biol Psychiatry. 1991;29:391–396
- . On kynureninase activity. Adv Exp Med Biol. 1991;294:523–526
- . Biochemical mechanisms affecting susceptibility to noise-induced hearing loss. Am J Otol. 1989;10:36–41
- . Enhanced stress responsitivity of Tourette syndrome patients undergoing lumbar puncture. Biological Psychiatry. 1994;36:35–43
- . Cerebrospinal fluid biogenic amines in obsessive compulsive disorder, Tourette's syndrome, and healthy controls. Neuropsychopharmacology. 1995;12:73–86
- . The interaction of some kynurenine pathway metabolites with 5-hydroxytryptophan and5-hydroxytryptamine. Psychopharmacology. 1977;51:305–309
- . Kynurenine may directly interact with GABA receptors in rat brain. Pharmacology. 1985;30:255–258
-
.
Excitatory effects of kynurenine and its metabolites, amino acids and convulsants administered into brain ventricles: differences between rats and mice.
Neural Transm. 1982;54:229–238
-
.
Amino acid neurotransmitters.
In:
Seigel GJ editors.
Basic Neurochemistry: Molecular, Cellular and Medical Aspects. New York: Raven Press; 1989;p. 311–332
-
.
Clonidine and clonazepam in Tourette syndrome.
In:
Chase TN, Friedhoff AJ, Cohen DJ editor.
Advances in Neurology, Vol. 58, Tourette Syndrome: Genetics, Neurobiology and Treatment. New York: Raven Press; 1992;p. 245–251
-
.
The use of benzodizepines in obsessive compulsive disorder and Tourette's syndrome.
Pyschiat Ann. 1993;23:417–424
- . GABAergic attenuation of cocaine-induced dopamine release and locomotor activity. Synapse. 1997;25:393–398
-
.
Association of Tourette-like syndrome with ofloxacin.
Annals of Pharmacotherapy. 1996;30:138–141
- . Intraventricular administration of I-kynurenine and kynuramine facilitates lordosis in the female rat. Eur J Pharmacol. 1987;142:447–451
- . Effect of magnesium deficiency on vitamin B2 and B6 status in the rat. J Am Coll Nutr. 1997;16:352–356
-
.
Vitamin B6 Metabolism and Role in Growth. Westport: Food & Nutrition Press Inc; 1980;
p. 151
-
.
Vitamin B6 Metabolism and Role in Growth. Westport: Food & Nutrition Press Inc; 1980;
p. 246–248
- . Neurogenic peptides and the cardiomyopathy of magnesium-deficiency: effects of substance P-receptor inhibition. Mol Cell Biochem. 1994;130:103–109
- . Comparison of tryptophan metabolism in vivo and in isolated hepatocytes from vitamin B6 deficient mice. Adv Exp Med Biol. 1991;294:359–368
- . L-kynurenine: its synthesis and possible regulatory function in brain. [Review]. Neurochemical Research. 1980;5:223–239
- . Blood serotonin and tryptophan in Tourette syndrome. Am J Med Genet. 1990;36:418–430
- . Exclusion of the 5-HT1A serotonin neuroreceptor and tryptophan oxygenase genes in a large British kindred multiply affected with Tourette's syndrome, chronic motor tics, and obsessive-compulsive behavior. Am J Psychiatry. 1995;152:437–440
-
.
The Role of Transaminations in Pharmacological Effects of Indole-3-Pyruvic Acid.
In:
Schwarcz R, Young SN, Brown RR editor.
Kynurenine and Serotonin Pathways. New York: Plenum Press; 1991;p. 603–606
-
.
The Merck Manual. Rahway: Merck Sharp & Dohme Research Laboratories; 1972;
p. 1091
- . Vitamin B6 modulates transcriptional activation by multiple members of the steroid hormone receptor superfamily. J Biol Chem. 1992;267:3819–3824
-
.
Modulation of steroid receptor-mediated gene expression by vitamin B6. [Review].
FASEB. 1994;8:343–349
- . Comparison of tryptophan metabolism in vivo and in isolated hepatocytes from vitamin B6 deficient mice. Adv Exp Med Biol. 1991;294:359–368
-
.
Vitamin B6 Metabolism and Role in Growth. Westport: Food & Nutrition Press Inc; 1980;
p. 301
-
.
Nutrition and the Brain. New York: Raven Press; 1979;
p. 206–211
- . Alterations in brainstem alpha 2 adrenoreceptor activity in pryidoxine-deficient rat model of hypertension. Neurosci Lett. 1990;111:201–205
- . Vitamin B-6 depletion followed by repletion with animal- or plant-source diets and calcium and magnesium metabolism in young women. Am J Clin Nutr. 1992;56:905–910
- . In vivo assessment of prevention of white-noise-induced siezure in magnesium-deficient rats by N-methyl-D-aspartate receptor blockers [published erratum appears in Epilepsy Res 1994; 18 (1): 89. Epilepsy Res. 1994;17:249–256
-
.
Neurobiology. Taking apart NMDA Receptors.
Nature. 1987;329:325–326
- . Unilateral block of NMDA receptors in the amygdala prevents predator stress-induced lasting increases in anxiety-like behavior and unconditioned startle – effective hemisphere depends on the behavior. Physiol Behav. 1999;65:739–751
- . Kynurenine metabolites of tryptophan: implications for neurologic diseases. [Review]. Neurology. 1990;40:691–695
- . [Biochemical studies on AIDS dementia complex-possible contribution of quinolinic acid during brain damage]. [Review] [Japanese]. Rinsho Byori. 1995;43:891–901
- . Glutametergic drugs exacerbate symptomatic behavior in a transgenic model of comorbid Tourette's syndrome and obsessive-compulsive disorder. Brain Res. 2000;877:23–30
-
.
Nicotinic Acid. New York: Marcel Dekker, Inc; 1983;
p. 27
- . Induction of indoleamine 2,3-dioxygenase in tumor cells transplanted into allogeneic mouse: interferon-gamma is the inducer. Adv Exp Med Biol. 1991;294:437–446
-
.
Hippocampal kynurenines as etiological factors in seizure disorders. [Review].
Polish J Pharmacol Pharm. 1987;39:485–494
- . [The role of nitrogen oxide in migraine attack]. Neurol Neurochir Pol. 1999;33:435–444
- . Activation of N-methyl-D-aspartate receptors in the feline retrorubral nucleus elicits orofacial dyskinesia. Eur J Pharmacol. 1998;349:23–31
- . Tourette syndrome: prediction of phenotypic variation in monozygotic twins by caudate nucleus D2 receptor binding. Science. 1996;273:1225–1227
- . The pharmacology of native N-methyl-D-aspartate receptor subtypes: different receptors control the release of different striatal and spinal transmitters. Prog Neuropsychopharmacol Biol Psychiatry. 1998;22:35–64
- . Glutamatergic regulation of haloperidol-induced c-fos expression in the rat striatum and nucleus accumbens. Neuroscience. 2001;102:391–399
- . Role of NMDA glutamate receptors in regulating D2 dopamine-dependent fos induction in the rat striatopallidal pathway. Brain Res. 1999;818:543–547
- . Molecular approaches to child psychopathology. Hum Biol. 1998;70:413–432
- . Immunoregulation by neuropeptides in magnesium deficiency: ex vivo effect of enhanced substance P production on circulating T lymphocytes from magnesium-deficient mice. Magnes Res. 1996;9:3–11
-
Pernow, B. Research on Tachykinins: Clinical Trends, Henry, J. L.Couture, R.Cuello, A. C.Pelletier, G.Quirion, R.Regoli, D. Substance P and Neurokinins, New York, Springer Verlag, 1987, 372, 378
- . Selective neurokinin NK1 and NK2 receptor agonists infused in the substantia nigra of the rat increase vacuous chewing. Eur J Pharmacol. 1993;235:177–181
- . Striatal substance P cell clusters coincide with the high density terminal zones of the discontinuous nigrostratal dopaminergic projection system in the cat: a study by combined immunohistochemistry and autoradiographic axon-tracing. Neuroscience. 1987;20:557–576
- . Dopamine, serotonin and tachykinin in self-injurious behavior. [Review]. Life Sciences. 1996;58:2367–2375
- . Distinct mechanism for antidepressant activity by blockade of central substance P receptors. Science. 1998;281:1640–1645
- . Effect of tachykinin receptor inhibition in the brain on cardiovascular and behavioral responses to stress. J Pharmacol Exp Ther. 1997;280:238–246
- . Testosterone regulates substance P within neurons of the medial nucleus of the amygdala, the bed nucleus of the stria terminalis and the medial preoptic area of the male golden hamster. Brain Res. 1992;590:18–28
- . Substance P as an immune modulator of anxiety. Neuroimmunomodulation. 1997;4:42–48
- . Anxiolytic action of a neurokinin1 receptor antagonist in the social interaction test. Pharmacol Biochem Behav. 1997;58:747–752
- . Anxiolytic-like action of neurokinin substance P administered systemically or into the nucleus basalis magnocellularis region. Eur J Pharmacol. 1998;354:123–133
- . Evidence that substance P is utilized in medial amygdaloid facilitation of defensive rage behavior in the cat. Brain Res. 1993;625:283–294
- . Neuropeptides accentuate interleukin-4 induced human immunoglobuline E Synthesis in vitro. Experimental Dermatology. 1996;5:38–44
-
.
Substance P induction of itch- associated response mediated by cutaneous NK1 tachykinin receptors in mice.
J Pharmacol Exp Ther. 1998;86:1140–1145
- . Effect of capsaicin as a neuropeptide-releasing substance on sneezing reflex in a type I allergic animal model. Int Arch Allergy Immunol. 1992;98:256–261
- . Sensory neurophysiology of the cough reflex. J Allergy Clin Immunol. 1996;98:S84–S89
-
.
Distribution and quantity of neuroendocrine markers in allergic rhinitis.
Acta Otolaryngol (Stockh). 1998;118:398–403
- . Substance P induces degranulation of mast cells and leukocyte adhesion to venular endothelium. Peptides. 1995;16:1447–1452
- . [Seasonal fluctuations of substance P and vasoactive intestinal peptide concentrations in nasal secretions of patients with nasal allergy to Japanese cedar pollen]. [Japanese]. Arerugi. 1992;41:1651–1657
-
.
Inhibitory effects of Substance P and carbachol on the saturable sodium-dependent uptake process myo-inositol in rat parotid gland.
J Pharmacol Exp Ther. 1991;258:638–646
- . Decreased myo-inositol uptake is associated with reduced bradykinin-stimulated phosphatidylinositol synthesis and diacylglycerol content in cultured neuroblastoma cells exposed to L-fucose. J Neurochem. 1994;62:147–158
- . Magnesium depletion impairs myocardial carbohydrate and lipid metabolism and cardiac bioenergietics and raises myocardial calcium content in-vivo: relationship to etiology of cardiac diseases. Biochem Mol Biol Int. 1994;40:1183–1190
- . Phosphoinositides as regulators in membrane traffic. Science. 1996;271:1533–1539
- . VII International Union of Pharmacology classification of receptors for5-hydroxytryptamine (serotonin). Pharmacol Rev. 1994;46:157–203
- . Efficacy and tolerability of serotonin transport inhibitors in obsessive-compulsive disorder. Arch Gen Psychiatry. 1995;52:53–60
- . Immunoregulation by neuropeptides in magnesium deficiency: ex vivo effect of enhanced substance P production on circulating T lymphocytes from magnesium-deficient mice. Magnes Res. 1996;9:3–11
- . Increased plasma kynurenine and its relationship to neopterin and tryptophan in Tourette's syndrome. Psychological Medicine. 1996;26:857–862
- . Plasma increase of interleukin-12 and interferon-gamma. Pathological significance in autism. J Neuroimmunol. 1996;66:143–145
- . Th1- and Th2- like cytokines in CD4+ and CD8+ T cells in autism. J Neuroimmunol. 1998;85:106–109
- . Cerebrospinal fluid cytokines in pediatric neuropsychiatric disease. J Immunol. 1997;159:2994–2999
- . Circulation lymphocyte subsets in obsessive compulsive disorder, major depression and normal controls. J Affect Disord. 1999;52:1–10
-
.
Audiogenic seizures in magnesium-deficient mice: effects of magnesium pyrrolidone-2-carboxylate, magnesium acetyltaurinate, magnesium chloride and vitamin B-6.
Magnesium Research. 1993;6:11–19
- . Subcutaneously applied magnesium protects reliably against quinolinate-induced N-methyl-D-aspartate (NMDA)-mediated neurodegeneration and convulsions in rats: are there therapeutical implications. Neurosci Lett. 1990;117:207–211
- . Protective effect of Crassostrea gigas extract on audiogenic seizures in magnesium deficient mice. Biomed Pharmacother. 1998;52:162–165
- . Mg2+ protects against PCP-induced cerebrovasospasms and vascular damage in rat brain. Magnes Trace Elem. 1990;9:44–46
- . Brain damage and myocardial dysfunction: protective effects of magnesium in the newborn pig. Ann Thorac Surg. 1998;65:1730–1736
- . Treatment of Tourette's syndrome with calcium antagonists. Clin Neuropharmacol. 1990;13:77–83
- . Role of magnesium in the pathogenesis and treatment of migraines. Clin Neurosci. 1998;5:24–27
- . [The effect of deficiency of selected bioelements on hyperactivity in children with certain specified mental disorders]. [Article in Polish]. Ann Acad Med Stetin. 1998;44:297–314
-
.
Controversies in the treatment of autistic children: vitamin and drug therapy. [Review].
Journal of Child Neurology. 1988;3:68–72
-
.
Comparison of tryptophan metabolism in vivo and in isolated hepatocytes from vitamin B6 deficient mice.
Advances in Experimental Medicine Biology. 1991;294:359–368
-
.
Effects of Tryptophan 2, 3-Dioxygenase Inhibitors in the Rat.
In:
Schwarcz R, Young SN, Brown RR editor.
Kynurenine and Serotonin Pathways. New York: Plenum Press; 1991;p. 281–288
-
.
Tryptophan transport into the liver of Vitamin B6-deficient rats.
In:
Filippini GA, Costa VL, Bertazzo A editor.
Recent Advances in Tryptophan Research. New York: Plenum Press; 1996;p. 589
- . Nicotinamide, inosine and hypoxanthine, putative endogenous ligands of the benzodiazepine receptor, opposite to diazepam are much more effective against kynurenine-induced seizures than against pentylenetetrazol- induced seizures. Pharmacol Biochem Behav. 1981;14:589–593
- . A double blind randomised placebo controlled trial of hexopal in primary Raynoud's disease. Clin Rheumatol. 1988;7:46–49
- . Magnesium content of erythrocytes in patients with vasospasic angina. Cardiovasc Drugs Ther. 1991;5:677–680
- . Clinical syndromes with vasoconstrictor response. Wien Klin Wochenschr. 1991;103:217–221
- . L-trytophan-induced eosinophilia- myalgia syndrome. II. Partial correction of abnormal tryptophan metabolism by pyridoxine. Dermatologica. 1991;183:62–65
- . Purification and characterization of mlothionein and its activation of pyridoxal phosphokinase in trout (Salmo gairdneri) brain. Comp Biochem Physiol [B]. 1993;104:293–298
- . Persistent Amphetamine-Induce Compulsive Rituals: Response to Pyridoxine (B6). Biological Psychiatry. 1981;16:583–587
- . Gilles de la Tourette syndrome. Interactions with other neuropsychiatric disorders. Acta Psychiatrica Scandinavica. 1979;59:9–16
-
.
Mg deficiency induces mineral content changes and oxidative stress in rats.
Biochemistry & Molecular Biology International. 1994;32:903–911
- . Impairment of ascorbic acid synthesis in liver extracts of magnesium-deficient rats. J Nutr. 1983;113:2041–2047
- . Enhanced NO production during Mg deficiency and its role in mediating red blood cell glutathione loss. Am J Physiol. 1996;271:C385–C390
- . Magnesium deficiency-induced cardiomyopathy: protection by vitamin E. Biochem Biophys Res Commun. 1990;170:1102–1106
- . Cytokines, neuropeptides, and reperfusion injury during magnesium deficiency. Ann N Y Acad Sci. 1994;723:246–257
- . Vitamin E treatment of tardive dyskinesia. Am J Psychiatry. 1993;150:1405–1407
-
.
Tardive dyskinesia, lipid peroxidation, and sustained amelioration with vitamin E treatment.
Int Clin Psychopharmacology. 1993;8:151–153
- . The specificity of proanthocyanidin-protein interactions. J Biol Chem. 1981;256:4494–4497
- . Inhibition by nicotinamide of antigen-induced histamine release from mouse peritonial mast cells. Int Arch Allergy Appl Immunol. 1976;50:729–736
- . [Effect of pyridoxine on histamine liberation and degranulation of rat mast cells]. Allergol Immunopathol (Madr). 1979;7:427–432
-
.
Inhibitory effects of tannins on hyaluronidase activation and on the degranulation from rat mesentery mast cells.
Chem Pharm Bull. 1985;33:5079–5082
- . Cardioprotective effects of grape seed proanthocyanidin against ischemic reperfusion injury. J Mol Cell Cardiol. 1999;31:1289–1297
- . Magnesium depletion impairs myocardial carbohydrate and lipid metabolism and cardiac bioenergietics and raises myocardial calcium content in-vivo: relationship to etiology of cardiac diseases. Biochem Mol Biol Int. 1994;40:1183–1190
- . The use of cholinergic precursors in neuropsychiatric diseases. Am J Clin Nutr. 1982;36:709–720
- . Myo-inositol reduces serotonin(5-HT2) receptor induced homologous and heterologous desensitization. Brain Res. 1993;631:349–351
- . Inositol Treatment of Obsessive-compulsive Disorder. Am J Psychiatry. 1996;153:1219–1221
- . Inositol treatment in psychiatry. [Review]. Psychopharmacol Bull. 1995;31:167–175
- . Changes of linoleic acid metabolism and cellular phospholipid fatty acid composition in LLC-PK cells cultured at low magnesium concentrations. Biochim Biophys Acta. 1989;1006:70–74
- . Loss of delta-6-desaturase activity as a key factor in aging. Medical Hypotheses. 1981;7:1211–1220
- . Essential fatty acid metabolism in boys with attention-deficit hyperactivity disorder. Am J Clin Nutr. 1995;62:761–768
- . Lowered omega3 polyunsaturated fatty acids in serum phospholiids and cholesteryl esters of depressed patients. Psychiatry Res. 1999;85:275–291
- . Lowered omega3 polyunsaturated fatty acids in serum phospholiids and cholesteryl esters of depressed patients. Psychiatry Res. 1999;85:275–291
- . Health Benefits of Docosahexaenoic Acid (DHA). Pharmacol Res. 1999;40:211–225
- . Dietary fish oil affects monoaminergic neurotransmission and behavior in rats. J Nutr. 1998;128:2512–2519
- . Red blood cell and tissue phospholipid fatty acid profiles of weanling rats fed infant formula fat blends containing soy and/or corn oil. Ann Nutr Metab. 1996;40:234–242
-
.
Tietz Textbook of Clinical Chemistry. Philadelphia: W. B. Saunders Company; 1994;
p. 1953–1954
- . Neurotic, neuromuscular and autonomic nervous form of magnesium imbalance. Magnes Res. 1997;10:169–195
PII: S0306-9877(01)91447-1
doi: 10.1054/mehy.2001.1447
© 2002 Elsevier Science Ltd. All rights reserved.
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Medical Hypotheses
Volume 58, Issue 1
, Pages 47-60
, January 2002
