Medical Hypotheses
Volume 58, Issue 2 , Pages 113-114 , February 2002

The role of maternal reproductive history in the aetiology of neural tube defects

  • S. Bianca

      Affiliations

    • Registro Siciliano Malformazioni Congenite, Catania, Italy
    • Dottorato di Ricerca in Malattie Genetiche dell'Età Evolutiva, Università di Catania, Catania, Italy
    • ,
  • M. Bianca

      Affiliations

    • Registro Siciliano Malformazioni Congenite, Catania, Italy
    • ,
  • F. Bonaffini

      Affiliations

    • Dipartimento Scienze Microbiologiche e Ginecologiche, Università di Catania, Catania, Italy
    • ,
  • G. Ettore

      Affiliations

    • Registro Siciliano Malformazioni Congenite, Catania, Italy
    • Dottorato di Ricerca in Malattie Genetiche dell'Età Evolutiva, Università di Catania, Catania, Italy
    • Dipartimento Scienze Microbiologiche e Ginecologiche, Università di Catania, Catania, Italy
    • Divisione di Ostetricia e Ginecologia, Azienda Ospedaliera Garibaldi, Catania, Italy

Received 8 February 2001 ,Accepted 5 July 2001.

References 

  1. Myrianthopoulos NC, Melnick M. Studies in neural tube defects. I. Epidemiologic and etiologic aspects. Am J Med Genet. 1987;26:783–796
  2. Seller MJ. Recurrence risk for neural tube defects in a genetic counseling clinic population. J Med Genet. 1981;18:245–248
  3. Rivas F, Dávalos IP, Olivares N. Reproductive history in mothers of children with neural tube defects. Gynecol Obstet Invest. 2000;49:255–260
  4. Castilla EE, Paz JE. Parity and Down's syndrome. Lancet. 1994;344:1645
  5. Kallen B. Parity and Down syndrome. Am J Med Genet. 1997;70:196–201
  6. Clementi M, Bianca S, Benedicenti F, Tenconi R. Working Group on Down Syndrome. Down syndrome and parity. Community Genet. 1999;2:18–22
  7. Buccimazza SS, Molteno CD, Dunne TT, Viljoen DL. Prevalence of neural tube defects in Cape Town, South Africa. Teratology. 1994;50:194–199
  8. Carmi R, Gohar J, Meizner I, Katz M. Spontaneous abortion: high risk factor for neural tube defect in subsequent pregnancy. Am J Med Genet. 1994;51:93–97
  9. Clarke C, Hobson D, McKendrick OM, Rogers SC, Sheppard PM. Spina bifida and anencephaly: miscarriage as possible cause. Br Med J. 1975;4:743–746
  10. Gardiner A, Clarke C, Cowen J, Finn R, McKendrick OM. Spontaneous abortion and f abnormality in subsequent pregnancy. Br Med J. 1978;1:1016–1018
  11. Knox E G. Fetus–fetus interaction, a model aetiology for anencephalus. Developmental Med and Child Neurol. 1970;12:167–177
  12. Bianca S, Ettore G, Guarnera S, Meli S, Mollica F. The relationship between congenital cardiovascular malformations and spontaneous abortion in preceding pregnancy (Letter). Paediatr Perinat Epidemiol. 1999;13:236

PII: S0306-9877(01)91468-9

doi: 10.1054/mehy.2001.1468

Medical Hypotheses
Volume 58, Issue 2 , Pages 113-114 , February 2002

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