Medical Hypotheses
Volume 58, Issue 3 , Pages 249-250, March 2002

Treatment of chronic fatigue syndrome by dietary supplementation with ω-3 fatty acids – a good idea?

Department of Research, Isfahan University of Medical Sciences, Isfahan, Iran

Received 28 November 2000; accepted 16 August 2001.

Abstract 

Minor alterations of immune, neuroendocrine, and autonomic function may be associated with the chronic fatigue syndrome. ω-3 fatty acids decrease the production of putative mediators of inflammation, including interleukin-1, and tumor necrosis factor. Since interleukin-1 and tumor necrosis factor are the principal polypeptide mediators of immunoregulation, reduced production of these cytokines by dietary supplementation with ω-3, may be a possible mechanism for the treatment of chronic fatigue syndrome.

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  • f1 Correspondence to: Dr Babak Tamizi far, Department of Education and Research, Shahrekord University of Medical Sciences, Shahrekord, Iran. Phone: +983125890; Fax: +983813335776; E-mail: babak360@yahoo.com

PII: S0306-9877(01)91507-5

doi:10.1054/mehy.2001.1507

Medical Hypotheses
Volume 58, Issue 3 , Pages 249-250, March 2002