Received 11 April 2001; accepted 22 November 2001.
Abstract
Cancer remains one of the leading causes of death throughout the world. One of the important reasons why conventional treatments fail is the development of resistance to therapeutics. The dual effect concept and self-defense mechanism plus the threshold theory might in part explain the development of resistance, however, the primary cause is unclear. A novel theory, `cell brain', where, selective crystallization of the `brain' of a cell (comprising centrosome, centrioles and the connecting filaments) occurs, may be a potential alternate approach to cancer therapy.
bKang-You MedPharm Research Institute, Jinan, China
cShandong University 21th Century Research Center, Jinan, China
Correspondence to: Qingzhong Kong MD, PhD, Cocid Corp, 799 Dahlia St., Denver, CO 80220, USA. Phone: (303)399-4185; Fax: (303)399-4185; Present address: Professor and Director, Cell Brain Research Center, South Biology Building, Room 128, Shandong University, East Campus, Jinan, Shandong Province 250100, China
ABSTRACT