Medical Hypotheses
Volume 59, Issue 1 , Pages 89-91 , July 2002

Role of selenium depletion in the effects of dialysis on mood and behavior

  • Leo Sher

      Affiliations

    • Corresponding Author InformationCorrespondence to: Leo Sher MD, 530 West 236th Street, #3N, Riverdale, NY 10463, USA

Received 13 June 2001 ,Accepted 1 November 2001.

References 

  1. Finkelstein FO, Finkelstein SH. Depression in chronic dialysis patients: assessment and treatment. Nephrol. Dial Transplant. 2000;15:1911–1913
  2. Finkelstein FO, Finkelstein SH. Psychological adaptation and quality of life of the patient with end-stage renal disease. In:  Brown E,  Parfrey P editor. Complications of Long Term Dialysis. Oxford: Oxford University Press; 1999;p. 168–187
  3. Kimmel PL, Thamer M, Richard C, Ray NF. Psychiatric illness in patients with end-stage renal disease. Am. J. Med. 1998;105:214–221
  4. Lowrie, E. G., Zhang, H., LePain, N., Lew, N., Lazarus, J. M. The association of SF-36 quality of life scales with patient mortality, CQI Memorandum, Fresenius Medical Care, 1997
  5. Kimmel PL, Weihs K, Peterson RA. Survival in hemodialysis patients: the role of depression. J. Am. Soc. Nephrol. 1993;4:12–27
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  7. Israel M. Depression in dialysis patients: a review of psychological factors. Can. J. Psychiatry. 1986;31:445–451
  8. Bogye G, Tompos G, Alfthan G. Selenium depletion in hemodialysis patients treated with polysulfone membranes. Nephron. 2000;84:119–123
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  10. Richard MJ, Ducros V, Foret M, Arnaud J, Coudray C, Fusselier M, et al. Reversal of selenium and zinc deficiencies in chronic hemodialysis patients by intravenous sodium selenite and zinc gluconate supplementation. Biol. Trace Elem. Res. 1993;39:149–159
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  12. Rayman MP. The importance of selenium to human health. Lancet. 2000;356:233–241
  13. Sanit-Georges MD, Bonnefont DJ, Bourely BA, Jaudon MC, Cereze P, Chaumeil P, et al.  Correction of selenium deficiency in hemodialyzed patients. Kidney Int. 1989;36(suppl. 27):s274–s277
  14. Hawkes WC, Hornbostel L. Effects of dietary selenium on mood in healthy men living in a metabolic research unit. Biol. Psychiatry. 1996;39:121–128
  15. Finley JW, Penland JG. Adequacy or deprivation of dietary selenium in healthy men: clinical and psychological findings. J. Trace Elem. Exp. Med. 1998;11:11–27
  16. Benton D, Cook R. Selenium supplementation improves mood in a double-blind crossover trial. Biol. Psychiatry. 1991;29:1092–1098
  17. Berr C, Balansard B, Arnaud J, Roussel AM, Alperovitch A. Cognitive decline is associated with systemic oxidative stress – the EVA study. J. Am. Geriat. Soc. 2000;48:1285–1291
  18. Koehrle J. The trace element selenium and the thyroid gland. Biochimie. 1999;81:527–533
  19. Sher L. Role of thyroid hormones in the effects of selenium on mood, behavior, and cognitive function. Med. Hypotheses: (in press)
  20. Sher L. Selenium and human health. Lancet. 2000;356:943
  21. Levy NB. Psychological problems of the patient on hemodialysis and their treatment. Psychother. Psychosom. 1979;31:260–266
  22. Itai T, Amayasu H, Kuribayashi M, Kawamura N, Okada M, Momose A, et al.  Psychological effects of aromatherapy in chronic hemodialysis patients. Psychiatry Clin. Neurosci. 2000;54:393–397

PII: S0306-9877(02)00129-9

Medical Hypotheses
Volume 59, Issue 1 , Pages 89-91 , July 2002

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