Medical Hypotheses
Volume 59, Issue 6 , Pages 630-635, 12 November 2002

Mesoderm layer and fibrous support tissues essential for embryological differentiation

  • Y Hirata

      Affiliations

    • Corresponding Author InformationCorrespondence to: Yoso Hirata M.D., Hirata Hospital, 5-4-23 Hommachi, 780-0870 Kochi, Nippon, Japan. Phone: +81-888-75-6221; Fax: +81-888-71-3801
  • ,
  • S Hirata

Hirata Hospital, Kochi, Nippon, Japan

Received 25 June 2001; accepted 13 February 2002.

Abstract 

Of the three germ layers, the mesoderm layer is the first to differentiate from the blastula and continues to lead the embryological differentiation while initiating the secretion of antagonistic duplication and maturation factors. After differentiation and while maintaining the secretion of duplication and maturation factors, the fibrous tissues that differentiated from mesoderm play an essential role in regulating the physio-mitotic conditions of functional tissues found in all histological organizations. Accordingly, some defects in mitotic interaction between the fibrous and functional tissues organized into structural units may give rise to various diseases such as carcinoma, sarcoma, leukemia, and fibro-multiplastic, myo-atrophic and neuroatrophic diseases. This defect in mitosis suggests the most important step in achieving eradication of these diseases.

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PII: S0306-9877(02)00160-3

Medical Hypotheses
Volume 59, Issue 6 , Pages 630-635, 12 November 2002