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Medical Hypotheses
Volume 59, Issue 6
, Pages 660-666
, 12 November 2002
A hypothesis of synergism: the interrelationship of T3 and insulin to disturbances in metabolic homeostasis
References
- . Glucose clamp techniques: a method for quantifying insulin secretion and resistance. Am. J. Physiol. 1979;237:E214–E223
-
.
Risk factors for NIDDM.
In: Diabetes in America. 2nd Edn.. 1995;p. 179–220
-
.
Fructose-2,3-biphosphate in control of hepatic gluconeogenesis: from metabolites to molecular genetics.
Diabetes Care. 1990;13:588–599
-
.
Association between polymorphism of the glycogen synthase gene and NIDDM.
N. Engl. J. Med. 1993;328:110–114
-
.
Metabolic regulation.
In:
Cohen RD, Lewis B, Albert KGMM, Denmann AM editor. The Metabolic and Molecular Basis of Acquired Diseases. London: Baillie’re Tindall; 1990;p. 300–320
-
.
Mechanism of thyroid hormone action.
In: Endocrinology. 3rd Edn.. Leslie Degroot, Philadelphia, PA: W. B. Saunders; 1995;p. 1–64
pp. 583–601
- . The genes of hepatic glucose metabolism. J. Biol. Chem. 1990;265:10173–10182
- . Stimulation of glucose transport by thyroid hormone in ARL.15 cells: increased abundance of glucose transporter protein and messenger RNA. Endocrinology. 1990;126:1421–1429
- . 3-Adrenergic receptor-mediated lipolysis and oxygen consumption in brown adipocytes from cynomologus monkeys. J. Clin. Endocrinol. Metab. 1997;82:395–401
-
.
Effect of thyroid state on a- and b-cathecholamine responsiveness of hamster.
Biochim. Biphys. Acta. 1981;678:334–341
-
.
Skeletal muscle triglyceride levels are inversely related to insulin action.
Diabetes. 1997;83–988
- . Thyroid hormones regulate G-protein B subunit mRNA expression in Vivo. J. Biol. Chem. 1989;264:16183–16189
-
Concept of the glucose-fatty acid cycle.
Ciba Found. Colloquia Endocrinol. 1964;15–19
- . Fuel selection in human skeletal muscle in insulin resistance. Diabetes. 2000;49:677–683
-
.
Nunez: cyclic AMP and lipogenesis in fat cells from thyroidectomized rats.
J. Mol. Cell. Endocrinol. 1979;14:167–169
- . The regulation of lipogenesis and its contribution to thermogenesis. Endocrinology. 1989;125:2868–2874
- . Cyclic nucleotides and lipogenesis in fat cell from thyroidectomized rats. J. Biol. Chem. 1978;253:671–678
-
Forciea M. A., Schwartz H. L., Towle H. C., Mariash C. N., Kaiser F. E., Oppenheimer J. H. Thyroid hormone-carbohydrate interaction in rat. 67: 1739–1747
-
.
Regulation of fetal muscle development by thyroxin.
Acta Anat. 1994;149(1):21–30
-
.
The effects of diabetes mellitus on thyroid physiology.
Thyroid Today. 1981;4:1–4
- . Thyroid function of the aged as viewed from the pituitary thyroid system. Endocrinol. JPN. 1979;21:377–384
-
.
Low serum thyroxin index in ambulatory elderly is due to a resetting of the threshold of thyrotropin feedback suppression.
J. Clin. Endocrinol. Metabolism. 1991;972X:0843–7304
-
.
In vivo stimulation of sugar uptake in rat thymocyte.
J. Clin. Inv. 1985;76:1575–1580
- . G-proteins and dual control of adenylate cyclase. Cell. 1984;36(40):577–579
-
.
G-proteins: a family of signal transducers.
Ann. Rev. Cell. Biol. 1986;2:391–419
- . Regulation of UCP-2 and 3 mRNA expression during lipid infusion in human skeletal muscle and subcutaneous adipose tissue. Diabetes. 2000;49:25–31
- . Uncoupling proteins 2 and 3; potential regulators of mitochondrial energy metabolism. Diabetes. 2000;49:143–156
- . Decreased tolbutamide-stimulated insulin secretion in healthy subjets with sequence variants in the high-affinity sulfonylurea receptor gene. Diabetes. 1998;47:598–605
- . Molecular biology of ATP-sensitive potassium channels. Endocr. Res. 1999;20:101–136
-
.
Thyroid and glucocorticoid homornes regulate the expression of multiple Na, K-ATPase genes in cultured neonatal rat cardiac myocytes.
J. Bio. Chem. 1990;265:3462–3470
-
.
Tissue-specific regulation of the a-myosin heavy chain gene promoter in transgenic mice.
J. Biol. Chem. 1991;256:24613–24620
-
.
Cyclic nucleotide phosphodiesterase in liver.
In:
Beavo JA, Houselay MD editor. Cycleic Nucleotide Phosphodiesterase: Structure, Regulation and Drug Action. Chichester, UK: Wiley; 1990;p. 185–223
- . Management of hyperglycemic crises in patients with diabetes. Diabetes Care. 2001;24:131–151
- . A1 and B-adrenergi agents cause synergistic stimulation of the lodothyronine Deiodinase in rat brown adiposities. Endocrinology. 1989;125:2502–2509 1999
-
.
Change in B1- and B2-adrenergic receptor mRNA levels in brown adipose tissue and heart of hypothyroid rats.
Biochem. J. 1991;277:625–629
- . The adenylate cyclase-cAMP system in islets of Langerhans and its role in the control of insulin release. Diabetologia. 1979;16:287–296
-
.
Altered insulin secretion associated with reduced lipolytic efficiency in a P2−/− mice.
Diabetes. 48:1987-1994;
- . Intramuscular triglyceride and muscle insulin sensitivity: evidence for relationship in nondiabetic subjects. Metabolisms. 1996;45:947–950
- . Molecular considerations relevant to the mechanism of active transport. Nature. 1981;292:201–204
-
.
Effect of thyroid hormones on glucokinase gene transcription in rat liver.
J. Biol. Chem. 1989;264:20647
-
.
Thyroid hormone stimulates expression of6-phosphofructo-2-kinase in rat liver.
FEBS Lett. 1989;267:211–214
- . Triiodothyronine-induced accumulations of malic enzyme, fatty acid synthase, acetyl-coA carboxylase, and their mRNAs are blocked by protein kinase inhibitors. Transcription is the affected step. J. Biol. Chem. 1991;266:17459–17466
-
.
Transcriptional and posttranscriptional regulation of rat hepatic 3-hydroxy-3-methylglutaryl-coenzyme A reductase by thyroid hormone receptor.
Proc. Natl. Acad. Sci. USA. 1987;84:3420–3425
- Role of thyroid hormones in apolipoprotein A-1 gene expression in rat liver. J. Clin. Invest. 1990;85:659–667
- . Acyl-CoA inhibition of hexokinase in rat and human skeletal muscle is a potential mechanism of lipid-induced insulin resistance. Diabetes. 2000;49:1761–1765
- . Subcutaneous abdominal fat and thigh muscle composition predict insulin sensitivity independently of visceral fat. Diabetes. 1997;46:1579–1595
-
Olesky J. M., Farquhar J. W., Raven G. M. Reappraisal of the role of insulin in hypertriglyceridemia. Am J Med 57: 551–560
- . Clearance of chylomicron triacylglycerol and cholesteryl ester from plasma of streptozin-induced diabetic and hypercholesterolemic hypothyroid rats. Metabolism. 1977;26:493–503
-
.
Defective fatty acid-mediated b-cell compensation in Zucker diabetic fatty acid rate pathogenic implication for obesity-dependent diabetes.
J. Biol. Chem. 1996;217:5633–5637
- . T3 regulation of TSH subunit gene transcription is proportional to T3 nuclear receptor occupancy. Endocrinology. 1986;118:367–371
- . Metabolic characteristics of individuals with impaired fasting glucose and/or impaired glucose. Diabetes. 1999;48:2197–2203
- . Uncoulping proteins 2mRNA expression during very-low-calorie-diet in obese premenopausal women. J. Clin. Endocrinol. Metab. 1998;83:2450–2453
- . Skeletal muscle uncoupling protein3 expression is a determination of energy expenditure in Pima Indians. Diabetes. 1999;48:146–149
- . Evidence of an increased number of type-2b muscle fibers in insulin resistant first-degree relatives of patients with NIDDM. Diabetes. 1997;46:1822–1828
-
.
Myosin structure and function in cell motility.
Ann. Rev. Cell. Biol. 1987;3:379–421
- . Skeletal muscle lipid content and oxidative enzyme activity in relation to muscle fiber type in type 2 diabetes and obesity. Diabetes. 2001;50:817–823
- . Skeletal muscle fatty acid metabolism in association with insulin resistance, obesity and weight loss. Am. J. Physiol. 1999;277:E1130–E1141
- . Altered glycolytic and oxidative capacities of skeletal muscle contributes to insulin resistance in NIDDM. J. Appl. Physiol. 1997;83:166–171
-
.
Skeletal muscle glycolytic and oxidative enzyme capacities of skeletal muscle composition in obese women.
FASEB J. 1996;9273–9278
-
Kim S. R., Talbott E. O., Tull E. S., Vogt M. T., Kuller L. H. Assessment of metabolic homeostasis. Med. Hypothesis (submitted)
PII: S0306-9877(02)00211-6
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Medical Hypotheses
Volume 59, Issue 6
, Pages 660-666
, 12 November 2002
