Medical Hypotheses
Volume 60, Issue 2 , Pages 298-303, February 2003

Correlation of mollicutes and their viruses with multiple sclerosis and other demyelinating diseases☆

  • James S Brown Jr.

      Affiliations

    • Corresponding Author InformationCorrespondence to: James S. Brown Jr MD, Director, Mental Health Clinic, McGuire Veterans Affairs Medical Center, 1201 Broad Rock Blvd., Richmond, VA 23249, USA. Phone: 1-804-675-5000x4208; Fax: 1-804-675-5678

McGuire Veterans Affairs Medical Center, Richmond, Virginia, USA

Received 25 January 2002; accepted 8 May 2002.

Abstract 

To identify infectious diseases likely involved in MS, the author previously correlated the geographical distribution of MS with the global distribution of tick-borne diseases. Tick-borne infectious agents include mollicutes or mycoplasmas. The current paper reviews evidence that mollicutes, especially spiroplasmas, or their viruses could be the initial exposure that causes MS. Mollicute infections, including the effects of their toxins, can be treated or prevented with gold salts or tetracyclines. If further research recommended by this review finds a role of mycoplasmas in MS, treatment of MS with gold with tetracycline should be evaluated.

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☆ Disclaimer: The opinions expressed herein are solely those of the author and do not purport to represent the opinions of the US Department of Veterans Affairs.

PII: S0306-9877(02)00390-0

Medical Hypotheses
Volume 60, Issue 2 , Pages 298-303, February 2003

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