Medical Hypotheses
Volume 62, Issue 1 , Pages 72-78, January 2004

Hypothetical hypercholesterolaemia and atherosclerosis☆

  • W.E Stehbens

      Affiliations

    • Corresponding Author InformationTel.: +64-4-385-5999; fax: +64-4-389-5725

Department of Pathology and Molecular Medicine, Wellington School of Medicine and Health Sciences, P.O. Box 7343, Wellington South, Wellington, New Zealand

Received 11 July 2002; accepted 11 November 2002.

Abstract 

Recent pathological advances in experimental and iatrogenic atherosclerosis and critical review of the epidemiology of coronary heart disease revealed fallacious data and methodological errors underlying the hypercholesterolaemia/lipid hypothesis. Misuse of risk factors, inappropriate use of surrogates and misinterpretation of data pertaining to cholesterol’s role in atherogenesis necessitate greater precision in word usage and terminology, reinstitution of the statistical reference range for cholesterol and closer scientific surveillance of aetiological endeavours in medicine.

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☆ Financial support was received from the Wellington Medical Research Foundation.

PII: S0306-9877(03)00267-6

doi:10.1016/S0306-9877(03)00267-6

Medical Hypotheses
Volume 62, Issue 1 , Pages 72-78, January 2004

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