Medical Hypotheses
Volume 73, Issue 3 , Pages 448-452, September 2009

Treatment of right ventricular dysfunction in pulmonary arterial hypertension: Theoretical considerations

  • Peter J. Engel

      Affiliations

    • Pulmonary Hypertension Clinic, The Christ Hospital, Cincinnati, OH, United States
    • Corresponding Author InformationCorresponding author. Address: The Lindner Center for Research and Education, 2123 Auburn Ave., Suite 424, Cincinnati, OH 45219, United States. Tel.: +1 513 382 6600; fax: +1 513 561 3781.
    • ,
  • Robert P. Baughman

      Affiliations

    • Department of Medicine, University of Cincinnati Medical Center, Cincinnati, OH, United States

Received 9 March 2009; accepted 12 March 2009. published online 27 May 2009.

Summary 

Significant progress has been made in the medical therapy of pulmonary hypertension in recent years, but long term results are still disappointing. We describe the theoretical underpinnings of a surgical procedure which we suggest might prevent or delay the occurrence of right ventricular failure and thereby improve long-term survival in pulmonary arterial hypertension. This is a hypothesis which could be tested in an animal model of this condition.

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PII: S0306-9877(09)00220-5

doi:10.1016/j.mehy.2009.03.029

Medical Hypotheses
Volume 73, Issue 3 , Pages 448-452, September 2009

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