Medical Hypotheses
Volume 51, Issue 6 , Pages 499-501, December 1998

On reciprocal translocations of chromatid segments in cancer cells

USC Medical School, 2011 Zonal Avenue, Los Angeles, CA 90033, USA

Received 5 August 1997; accepted 9 September 1997.

Abstract 

The paper discusses the dynamics of reciprocal translocations between chromatids in general terms. The mechanism accounts for the high frequency of these anomalies in cancer cells with nuclei distorted by permanent or transient deformations of their envelopes.

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PII: S0306-9877(98)90072-X

Medical Hypotheses
Volume 51, Issue 6 , Pages 499-501, December 1998

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