Medical Hypotheses
Volume 54, Issue 1 , Pages 47-50, January 2000

Repositioning of entangled chromatin during separation of sister chromatids by eversion

USC Medical School, Los Angeles, U.S.A.

Received 5 August 1998; accepted 25 August 1998.

Revised

Abstract 

We investigate how chromatin entanglements may subvert the topology of DNA segments (and of genes therein) whenever sister chromatids separate by eversion. Such subversions offer interesting ideas on how identical genes may be differently or identically expressed after segregation of sister chromatids.

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PII: S0306-9877(98)90826-X

doi:10.1054/mehy.1998.0826

Medical Hypotheses
Volume 54, Issue 1 , Pages 47-50, January 2000