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Medical Hypotheses
Volume 56, Issue 1, Pages 1-127 (January 2001)
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Regular Article


Up-regulation of hepatic IGFBP-1 production as a strategy for preventing benign prostatic hyperplasia
M.F. McCarty
pages 1-4
Abstract | Abstract + References | Full-Text PDF (66 KB)


Supplemental creatine may decrease serum homocysteine and abolish the homocysteine ‘gender gap’ by suppressing endogenous creatine synthesis
M.F. McCarty
pages 5-7
Abstract | Abstract + References | Full-Text PDF (57 KB)


Inhibition of CYP2E1 with natural agents may be a feasible strategy for minimizing the hepatotoxicity of ethanol
M.F. McCarty
pages 8-11
Abstract | Abstract + References | Full-Text PDF (66 KB)


Suppression of dolichol synthesis with isoprenoids and statins may potentiate the cancer-retardant efficacy of IGF-I down-regulation
M.F. McCarty
pages 12-16
Abstract | Abstract + References | Full-Text PDF (76 KB)


Obstructive sleep apnea and hypertension: are peripheral chemoreceptors involved?
J.S. Loredo, J.L. Clausen, R.A. Nelesen, S. Ancoli-Israel, M.G. Ziegler, J.E. Dimsdale
pages 17-19
Abstract | Abstract + References | Full-Text PDF (57 KB)


Psychiatric aspects of jet lag: review and hypothesis
G. Katz, R. Durst, Y. Zislin, Y. Barel, H.Y. Knobler
pages 20-23
Abstract | Abstract + References | Full-Text PDF (67 KB)


Viral inoculation for prophylaxis of polyoma virus associated diseases
E.L. Altschuler
pages 24-25
Abstract | Abstract + References | Full-Text PDF (40 KB)


Theory of cell membrane organizers and pressure reversal of anesthesia
M. Jibu
pages 26-32
Abstract | Abstract + References | Full-Text PDF (73 KB)


Radiogenic metabolism: an alternative cellular energy source
M.S. Benford
pages 33-39
Abstract | Abstract + References | Full-Text PDF (104 KB)


The cytological implications of primary respiration
P.N Crisera
pages 40-51
Abstract | Abstract + References | Full-Text PDF (235 KB)


Cell darwinism, apoptosis, free radicals and haematological malignancies
A. Cucuianu
pages 52-57
Abstract | Abstract + References | Full-Text PDF (114 KB)


Polyploidization: a Janus-faced mechanism
R.G. Hanselmann, M. Oberringer
pages 58-64
Abstract | Abstract + References | Full-Text PDF (116 KB)


A hypothesis accounting for the inconsistent benefit of glucocorticoid therapy in closed head trauma
M.K. Borsody, M.L. Coco
pages 65-72
Abstract | Abstract + References | Full-Text PDF (111 KB)


Porphyria: the road not traveled
D. Downey
pages 73-76
Abstract | Abstract + References | Full-Text PDF (72 KB)


The no-fault flavor of disability syndromes
R. Ferrari, O. Kwan
pages 77-84
Abstract | Abstract + References | Full-Text PDF (90 KB)


Maternal plasma homocysteine levels in women with preterm premature rupture of membranes
S.E. Ferguson, G.N. Smith, M.C. Walker
pages 85-90
Abstract | Abstract + References | Full-Text PDF (100 KB)


Hypothesized treatment for migraines using low doses of tryptophan, niacin, calcium, caffeine, and acetylsalicylic acid
A. Gedye
pages 91-94
Abstract | Abstract + References | Full-Text PDF (62 KB)


The role of uric acid in protection against peroxynitrite-mediated pathology
G.S. Scott, D.C. Hooper
pages 95-100
Abstract | Abstract + References | Full-Text PDF (103 KB)


The fetal antigen hypothesis: cancers and beyond
D.T. Janerich
pages 101-103
Abstract | Abstract + References | Full-Text PDF (52 KB)


Effects of seasonal mood changes on seasonal variations in coronary heart disease: role of immune system, infection, and inflammation
L. Sher
pages 104-106
Abstract | Abstract + References | Full-Text PDF (56 KB)


The physiological role of estriol during human fetal development is to act as antioxidant at lipophilic milieus of the central nervous system
M.A. Reyes-Romero
pages 107-109
Abstract | Abstract + References | Full-Text PDF (72 KB)


Model of cardiovascular injury in magnesium deficiency
K. Shivakumar
pages 110-113
Abstract | Abstract + References | Full-Text PDF (61 KB)


Antidenaturant drugs for cataract and other condensation diseases
L. Saso, B. Silvestrini
pages 114-120
Abstract | Abstract + References | Full-Text PDF (110 KB)


Causes of Alzheimer’s disease: paracetamol (acetaminophen) today? Amphetamines tomorrow?
G.R.N. Jones
pages 121-123
Abstract | Abstract + References | Full-Text PDF (53 KB)


Alzheimer’s disease: a review concerning immune response and microischemia
R.L. Chorsky, F. Yaghmai, W.D. Hill, E.G. Stopa
pages 124-127
Abstract | Abstract + References | Full-Text PDF (446 KB)

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