Medical Hypotheses

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Medical Hypotheses

Volume 64, Issue 6, Pages 1073-1250 (2005)

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AMPK activation as a strategy for reversing the endothelial lipotoxicity underlying the increased vascular risk associated with insulin resistance syndrome, 19 August 2004
Mark F. McCarty
pages 1211-1215
Abstract | Full Text | Full-Text PDF (158 KB)

Chromium picolinate may favorably influence the vascular risk associated with smoking by combating cortisol-induced insulin resistance, 19 August 2004
Mark F. McCarty
pages 1220-1224
Abstract | Full Text | Full-Text PDF (159 KB)

High mitochondrial redox potential may promote induction and activation of UCP2 in hepatocytes during hepatothermic therapy, 19 August 2004
Mark F. McCarty
pages 1216-1219
Abstract | Full Text | Full-Text PDF (143 KB)

“Starve a fever and feed a cold”: feeding and anorexia may be adaptive behavioral modulators of autonomic and T helper balance, 23 November 2004
Kimberly A. Bazar, A. Joon Yun, Patrick Y. Lee
pages 1080-1084
Abstract | Full Text | Full-Text PDF (251 KB)

The influence of weather and environment on pulmonary embolism: pollutants and fossil fuels, 31 December 2004
Ralf Clauss, Julian Mayes, Paul Hilton, Ross Lawrenson
pages 1198-1201
Abstract | Full Text | Full-Text PDF (92 KB)

Preventive and curative effects of probiotics in atopic patients, 04 January 2005
G.P.A. Bongaerts, R.S.V.M. Severijnen
pages 1089-1092
Abstract | Full Text | Full-Text PDF (78 KB)

Primary nocturnal enuresis: omega-3 fatty acids may be of therapeutic value, 31 December 2004
Alan C. Logan, Francois Lesperance
pages 1188-1191
Abstract | Full Text | Full-Text PDF (82 KB)

Motion sickness is linked to nystagmus-related trigeminal brain stem input: a new hypothesis, 13 January 2005
Vinod Kumar Gupta
pages 1177-1181
Abstract | Full Text | Full-Text PDF (94 KB)

Transplanted human embryonic stem cells as biological ‘catalysts’ for tissue repair and regeneration, 31 December 2004
Boon Chin Heng, Hua Liu, Tong Cao
pages 1085-1088
Abstract | Full Text | Full-Text PDF (77 KB)

Significant reduction of the risk of venous thromboembolism in all long term immobile patients a few months after the onset of immobility, 04 January 2005
Tarek A.-Z.K. Gaber
pages 1173-1176
Abstract | Full Text | Full-Text PDF (76 KB)

Selective reduction of estrogen receptor (ER) positive breast cancer occurrence by estrogen receptor modulators supports etiological distinction between ER positive and ER negative breast cancers, 31 December 2004
Sven Kurbel
pages 1182-1187
Abstract | Full Text | Full-Text PDF (84 KB)

Novel hypothesis for the cause of panic disorder via the neuroepithelial bodies in the lung, 04 January 2005
K. Fukuda
pages 1192-1197
Abstract | Full Text | Full-Text PDF (139 KB)

Lysosomal and prostasomal hydrolytic enzymes and redox processes and initiation of prostate cancer, 21 February 2005
Al Tappel
pages 1170-1172
Abstract | Full Text | Full-Text PDF (64 KB)

Reconstruction of the anterior cruciate ligament with a Patella–Tendon–Bone graft may lead to a permanent loss of bone mineral content due to decreased patellar tendon stiffness, 19 January 2005
Joern Rittweger, Nicola Maffulli, Constantinos N. Maganaris, Marco V. Narici
pages 1166-1169
Abstract | Full Text | Full-Text PDF (83 KB)

Hypothesis: A motor neuron toxin produced by a clostridial species residing in gut causes ALS, 19 January 2005
W.T. Longstreth, J.S. Meschke, S.K. Davidson, L.M. Smoot, J.C. Smoot, T.D. Koepsell
pages 1153-1156
Abstract | Full Text | Full-Text PDF (96 KB)

The smoking gun: many conditions associated with tobacco exposure may be attributable to paradoxical compensatory autonomic responses to nicotine, 19 January 2005
Anthony J. Yun, Kimberly A. Bazar, Patrick Y. Lee, Anthony Gerber, Stephanie M. Daniel
pages 1073-1079
Abstract | Full Text | Full-Text PDF (119 KB)

Selenium supplementation may increase the efficacy of cetuximab in metastatic colorectal cancer patients, 04 February 2005
Kadri Altundag, Yavuz S. Silay, Ozden Altundag, Orhan G. Yigitbasi, Ozlem Gundeslioglu, Mehmet Gunduz
pages 1162-1165
Abstract | Full Text | Full-Text PDF (83 KB)

A hypothesis matrix for studying biomechanical factors associated with the initiation and progression of posttraumatic osteoarthritis, 19 January 2005
Ashvin Thambyah
pages 1157-1161
Abstract | Full Text | Full-Text PDF (92 KB)

Correspondence

A rationale for the development of resistance to adriamycin (doxorubicin), 17 January 2005
Subburaj Kannan
pages 1238-1239
Full Text | Full-Text PDF (35 KB)

Possible metabolism – body weight effect on prolongation and reduction of the pregnancy duration, 02 February 2005
Atanas Todorov Atanasov
pages 1247-1248
Full Text | Full-Text PDF (40 KB)

Melatonin seems to be a mediator that transfers the environmental stimuli to oocytes for inheritance of adaptive changes through epigenetic inheritance system, 28 January 2005
M.K. Irmak, T. Topal, S. Oter
pages 1138-1143
Abstract | Full Text | Full-Text PDF (96 KB)

Correspondence

Short small bowel patients are permanently disabled due to unrecognised starvation, 31 January 2005
Ger Bongaerts, René Severijnen
pages 1249-1250
Full Text | Full-Text PDF (43 KB)

The potential utility of sodium valproate as a novel addition to anti-multiple myeloma armamentarium, 04 February 2005
M.R. Namazi
pages 1246-1247
Full Text | Full-Text PDF (41 KB)

The anti-inflammatory and antioxidant effects of long-chain n−3 fatty acids or oil-rich fish may favorably affect atrial remodeling in atrial fibrillation, 31 January 2005
Panagiotis Korantzopoulos, Theofilos M. Kolettis, John A. Goudevenos
pages 1245-1246
Full Text | Full-Text PDF (41 KB)

Fludarabine phosphate may be useful in the treatment of graft-versus-host disease, 07 March 2005
Sercan Aksoy, Huseyin Abali, Saadettin Kilickap, Murat Dinçer, Mustafa Erman
pages 1150-1152
Abstract | Full Text | Full-Text PDF (66 KB)

Uncertainties in the current understanding of gas exchange in spontaneous pneumothorax: effective lung ventilation may persist in a smaller-sized pneumothorax, 07 February 2005
D. Subotic, D. Mandaric, M. Gajic, M. Vukcevic
pages 1144-1149
Abstract | Full Text | Full-Text PDF (228 KB)

The empirical relationship between longevity and physical stature may be obscured by unobserved genetic diversity in the optimal metabolic rate, 07 February 2005
Marco Sunder
pages 1225-1228
Abstract | Full Text | Full-Text PDF (106 KB)

Tranilast: A novel weapon against insulin resistance, 07 February 2005
M.R. Namazi, J. Soma
pages 1135-1137
Abstract | Full Text | Full-Text PDF (71 KB)

The chemical reactions in the human stomach and the relationship to metabolic disorders, 08 April 2005
D.S. Robertson
pages 1127-1131
Abstract | Full Text | Full-Text PDF (92 KB)

Smoking promotes pathogenesis of aortic aneurysm through the 5-lipoxygenase pathway, 08 April 2005
Hisato Takagi, Takuya Umemoto
pages 1117-1119
Abstract | Full Text | Full-Text PDF (73 KB)

Treatment of acute lymphocytic leukemia using zinc adjuvant with chemotherapy and radiation – a case history and hypothesis, 21 February 2005
George A. Eby
pages 1124-1126
Abstract | Full Text | Full-Text PDF (69 KB)

The role of experimental myringosclerosis in interpretation of tympanograms and its possible clinical implications, 21 February 2005
Kazikdas K. Cagdas
pages 1132-1134
Abstract | Full Text | Full-Text PDF (70 KB)

A novel role for parkin in trauma-induced central nervous system secondary injury, 21 February 2005
K. Mukhida, N.R. Kobayashi, I. Mendez
pages 1120-1123
Abstract | Full Text | Full-Text PDF (87 KB)

Correspondence

Therapy of newly emerging mutant viral disorders and role in bioterrorism, 07 March 2005
J.L. Ambrus, J.L. Ambrus, C.M. Ambrus
pages 1248-1249
Full Text | Full-Text PDF (37 KB)

Is atrial fibrillation an inflammatory disease?, 21 February 2005
Tong Liu, Guangping Li
pages 1237-1238
Full Text | Full-Text PDF (49 KB)

Association of skin rash and tumor response to HER1/EGFR inhibition: Does HER1 stimulated tumor growth depend on circulatory instead of paracrine ligands?, 21 February 2005
Sven Kurbel, Dario Faj
pages 1244-1245
Full Text | Full-Text PDF (39 KB)

DNA methylation and the central dogma of molecular biology, 16 February 2005
Jacob Peedicayil
pages 1243-1244
Full Text | Full-Text PDF (38 KB)

Cardiac torsion and electromagnetic fields: The cardiac bioinformation hypothesis, 01 March 2005
Katharine O. Burleson, Gary E. Schwartz
pages 1109-1116
Abstract | Full Text | Full-Text PDF (237 KB)

Pathophysiology of capillary haemangioma growth after birth, 01 March 2005
Abderrahmane Hamlat, Mahmoudreza Adn, Edouardo Pasqualini, Gilles Brassier, Brahim Askar
pages 1093-1096
Abstract | Full Text | Full-Text PDF (80 KB)

Making cell-permeable antibodies (Transbody) through fusion of protein transduction domains (PTD) with single chain variable fragment (scFv) antibodies: Potential advantages over antibodies expressed within the intracellular environment (Intrabody), 01 March 2005
Boon Chin Heng, Tong Cao
pages 1105-1108
Abstract | Full Text | Full-Text PDF (79 KB)

Assessing the efficacy of antidepressants: The transactional paradigm, 01 March 2005
U.B. Wolfaardt, J.R. Reddon, A.S. Joyce
pages 1229-1236
Abstract | Full Text | Full-Text PDF (117 KB)

Correspondence

Can the high nuclear to cytoplasmic ratio of human embryonic stem cells make them more vulnerable to physical stress encountered with bulk-passage protocols?, 01 March 2005
Boon Chin Heng, Hua Liu, Tong Cao
pages 1242-1243
Full Text | Full-Text PDF (38 KB)

Denervation–reinnervation – hypothesis well-founded but not sufficient, 01 March 2005
Piotr Laudanski
pages 1241-1242
Full Text | Full-Text PDF (36 KB)

Met72Thr polymorphism of pigment epithelium-derived factor gene and susceptibility to age-related macular degeneration, 01 March 2005
S. Yamagishi, K. Nakamura, H. Inoue, M. Takeuchi
pages 1202-1204
Abstract | Full Text | Full-Text PDF (66 KB)

Developments

The possible use of arsine (AsH3) as therapy for malaria, 01 March 2005
George E. Parris
pages 1100-1101
Abstract | Full Text | Full-Text PDF (65 KB)

Correspondence

Mathematical model for polygenic diseases, 01 March 2005
Soumitra Shankar Datta
pages 1240-1241
Full Text | Full-Text PDF (39 KB)

Possible participation of advanced glycation end products in the pathogenesis of colorectal cancer in diabetic patients, 01 March 2005
S. Yamagishi, K. Nakamura, H. Inoue, S. Kikuchi, M. Takeuchi
pages 1208-1210
Abstract | Full Text | Full-Text PDF (72 KB)

Asthma: A disuse contracture?, 01 March 2005
C.J. Alexander
pages 1102-1104
Abstract | Full Text | Full-Text PDF (72 KB)

Serum or cerebrospinal fluid levels of glyceraldehyde-derived advanced glycation end products (AGEs) may be a promising biomarker for early detection of Alzheimer’s disease, 01 March 2005
S. Yamagishi, K. Nakamura, H. Inoue, S. Kikuchi, M. Takeuchi
pages 1205-1207
Abstract | Full Text | Full-Text PDF (74 KB)

Correspondence

Bisphosphonates may inhibit development of atherosclerosis formation through its bactericidal effect on nanobacteria, 01 March 2005
Yavuz S. Silay, Kadri Altundag, Ozden Altundag, Mustafa A. Atik, Mustafa Ozen
pages 1239-1240
Full Text | Full-Text PDF (39 KB)

Site specific therapy: An integrative approach to treating melanoma, 07 March 2005
Manuel Kavekos
pages 1097-1099
Abstract | Full Text | Full-Text PDF (67 KB)

Editorial board
page i
Full-Text PDF (108 KB)

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