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Medical Hypotheses
Volume 65, Issue 1, Pages 1-204 (2005)
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Personality profiles of normal healthy research volunteers: a potential concern for clinical drug trial investigators?, 07 March 2005
Carl L. Tishler, Suzanne Bartholomae, Angel R. Rhodes
pages 1-7
Abstract | Full Text | Full-Text PDF (116 KB)


The sweet thing about Type 1 diabetes: A cryoprotective evolutionary adaptation, 29 March 2005
S. Moalem, K.B. Storey, M.E. Percy, M.C. Peros, D.P. Perl
pages 8-16
Abstract | Full Text | Full-Text PDF (334 KB)


Forecasting versus projection models in epidemiology: The case of the SARS epidemics, 29 March 2005
Eduardo Massad, Marcelo N. Burattini, Luis F. Lopez, Francisco A.B. Coutinho
pages 17-22
Abstract | Full Text | Full-Text PDF (159 KB)


The scavenger cell hypothesis of apoptosis: Apoptosis redefined as a process by which a cell in living tissue is destroyed by phagocytosis, 29 March 2005
D. Joshua Liao
pages 23-28
Abstract | Full Text | Full-Text PDF (94 KB)


Are vasoactive neuropeptide autoimmune fatigue-related disorders mediated via G protein-coupled receptors?, 21 April 2005
Donald Staines
pages 29-31
Abstract | Full Text | Full-Text PDF (70 KB)


p53 Protein is activated by Pin1: And also by Cu-SOD prion-like enzyme, 13 April 2005
Alan Wiseman
pages 32-34
Abstract | Full Text | Full-Text PDF (75 KB)


PPARα activators may be good candidates as antiaging agents, 29 March 2005
Adnan Erol
pages 35-38
Abstract | Full Text | Full-Text PDF (116 KB)


Are treatment emergent suicidality and decreased response to antidepressants in younger patients due to bipolar disorder being misdiagnosed as unipolar depression?, 29 March 2005
Michael Berk, Seetal Dodd
pages 39-43
Abstract | Full Text | Full-Text PDF (88 KB)


The paradox of HIV nef function: Resolution of the contradictions, 29 March 2005
Richard Sallie
pages 44-46
Abstract | Full Text | Full-Text PDF (162 KB)


Risk analysis of ectoparasites acting as vectors for chronic wasting disease, 30 March 2005
Omar Lupi
pages 47-54
Abstract | Full Text | Full-Text PDF (134 KB)


Dysfunction of the anterior hippocampus: The cause of fundamental schizophrenic symptoms?, 29 March 2005
J. David Johnson
pages 55-60
Abstract | Full Text | Full-Text PDF (93 KB)


RISUG™ (reversible inhibition of sperm under guidance) – An antimicrobial as male vas deferens implant for HIV free semen, 30 March 2005
Sujoy K. Guha
pages 61-64
Abstract | Full Text | Full-Text PDF (136 KB)


Using histamine (H1) antagonists, in particular atypical antipsychotics, to treat anemia of chronic disease via interleukin-6 suppression, 29 March 2005
Eric Lewin Altschuler, Richard E. Kast
pages 65-67
Abstract | Full Text | Full-Text PDF (62 KB)


Does clozapine work by blocking spikes and sparing bursts?, 06 April 2005
Timothy P. Olson
pages 68-78
Abstract | Full Text | Full-Text PDF (264 KB)


Is autism caused by early hyperactivity of brain-derived neurotrophic factor?, 29 March 2005
Shih-Jen Tsai
pages 79-82
Abstract | Full Text | Full-Text PDF (77 KB)


The role of vestibular system and the cerebellum in adapting to gravitoinertial, spatial orientation and postural challenges of REM sleep, 29 March 2005
Nataraj E. Dharani
pages 83-89
Abstract | Full Text | Full-Text PDF (111 KB)


Unifying mechanism for addiction and toxicity of abused drugs with application to dopamine and glutamate mediators: Electron transfer and reactive oxygen species, 29 March 2005
Peter Kovacic
pages 90-96
Abstract | Full Text | Full-Text PDF (118 KB)


Will corticosteroids and other anti-inflammatory agents be effective for diarrhea-predominant irritable bowel syndrome?, 13 April 2005
Victor Crentsil
pages 97-102
Abstract | Full Text | Full-Text PDF (101 KB)


Enhancing anti-inflammatory cytokine IL-10 may be beneficial for acute coronary syndrome, 29 March 2005
Jian-Jun Li, Yuan-Lin Guo, Yue-Jin Yang
pages 103-106
Abstract | Full Text | Full-Text PDF (82 KB)


Dominant and opportunistic leukemic clones: Proposal for a pathogenesis-oriented classification in acute myeloid leukemia, 11 March 2005
Andrei Cucuianu
pages 107-113
Abstract | Full Text | Full-Text PDF (105 KB)


Migraine prophylactic drugs work via ion channels, 10 March 2005
Gary L. Cohen
pages 114-122
Abstract | Full Text | Full-Text PDF (125 KB)


Alzheimer’s disease and the ‘ABSENT’ hypothesis: mechanism for amyloid β endothelial and neuronal toxicity, 11 March 2005
Samir Roy, Arvi Rauk
pages 123-137
Abstract | Full Text | Full-Text PDF (466 KB)


5-Hydroxytryptophan plus SSRIs for interferon-induced depression: Synergistic mechanisms for normalizing synaptic serotonin, 09 March 2005
Erick H. Turner, Aaron D. Blackwell
pages 138-144
Abstract | Full Text | Full-Text PDF (151 KB)


Are cardiac syndrome X, irritable bowel syndrome and reflex sympathetic dystrophy examples of lateral medullary ischaemic syndromes?, 29 March 2005
Paul Syme
pages 145-148
Abstract | Full Text | Full-Text PDF (149 KB)


Concept-matching in the brain depends on serotonin and gamma-frequency shifts, 01 March 2005
M.B. Bayly
pages 149-151
Abstract | Full Text | Full-Text PDF (72 KB)


Inhibition of postprandial hyperglycemia by acarbose is a promising therapeutic strategy for the treatment of patients with the metabolic syndrome, 31 January 2005
S. Yamagishi, K. Nakamura, M. Takeuchi
pages 152-154
Abstract | Full Text | Full-Text PDF (65 KB)


Unique atheroprotective property of azelnidipine, a dihydropyridine-based calcium antagonist, 31 January 2005
K. Nakamura, S. Yamagishi, H. Inoue
pages 155-157
Abstract | Full Text | Full-Text PDF (68 KB)


Proposed multigenic Composite Inheritance in major depression, 29 March 2005
Katherine A. Raymer, Robert F. Waters, Catherine R. Price
pages 158-172
Abstract | Full Text | Full-Text PDF (155 KB)


The dynamic range of biologic functions and variation of many environmental cues may be declining in the modern age: implications for diseases and therapeutics, 06 January 2005
Anthony J. Yun, Kimberly A. Bazar, Anthony Gerber, Patrick Y. Lee, Stephanie M. Daniel
pages 173-178
Abstract | Full Text | Full-Text PDF (100 KB)


Male reproductive physiology as a sexually selected handicap? Erectile dysfunction is correlated with general health and health prognosis and may have evolved as a marker of poor phenotypic quality, 09 March 2005
Alessandro Cellerino, Emmanuele A. Jannini
pages 179-184
Abstract | Full Text | Full-Text PDF (99 KB)


Kaiser Wilhelm syndrome: Obstetric trauma or placental insult in a historical case mimicking Erb’s palsy, 24 March 2005
Venu Jain, Neil J. Sebire, David G. Talbert
pages 185-191
Abstract | Full Text | Full-Text PDF (593 KB)

Correspondence


Should we use digit preference as an indicator of quality control?, 09 March 2005
Li-Jian Li, Tong Liu, Pei-Shan Wang
pages 192-193
Full Text | Full-Text PDF (54 KB)


On the similarity of cocaine and 3,3′-iminodipropionitrile, 15 April 2005
Jordi Llorens
page 193
Full Text | Full-Text PDF (33 KB)


Pure and mixed hormone receptor positive breast tumors: Are they different from therapeutic point of view?, 20 April 2005
Kadri Altundag, Ozden Altundag, Esra Gunduz, Yavuz S. Silay, Cem Boruban
page 194
Full Text | Full-Text PDF (29 KB)


How to understand autistic motivational status, 20 April 2005
Fei Chen
page 195
Full Text | Full-Text PDF (31 KB)


Prostaglandin E (PgE) therapy for interstitial cystitis, 22 April 2005
Norman A. Smith
page 196
Full Text | Full-Text PDF (30 KB)


Atavistic orofacial response to manually dextrous activities, 29 March 2005
Arunachalam Kumar, Jairaj C. Kumar
page 196
Full Text | Full-Text PDF (30 KB)


A cybernetic theory of aging, 13 April 2005
Eugene Kaellis
page 197
Full Text | Full-Text PDF (31 KB)


Neutrophil chemotaxis: Autotaxin induced attenuation of purine/pyrimidine signaling precede the overexpression of Integrin(s), 21 February 2005
Subburaj Kannan
pages 197-198
Full Text | Full-Text PDF (38 KB)


Nanotechnology helps medicine: Nanoscale swimmers and their future applications, 09 March 2005
Zahra Ghalanbor, Sayed-Amir Marashi, Bijan Ranjbar
pages 198-199
Full Text | Full-Text PDF (38 KB)


Making cell-permeable recombinant telomerase (trans-telomerase) through fusion of its catalytic subunit (hTERT) with protein transduction domains (PTD): A possible strategy to overcome replicative senescence during ex vivo culture of primary explanted cells, 09 March 2005
Boon Chin Heng, Tong Cao
pages 199-200
Full Text | Full-Text PDF (37 KB)


Anti-inflammatory effects of long-chain ω3 fatty acids: Potential benefits for atrial fibrillation, 09 March 2005
Tong Liu, Guangping Li
pages 200-201
Full Text | Full-Text PDF (39 KB)


Transcendental meditation does not predispose to epilepsy, 09 March 2005
David W. Orme-Johnson
pages 201-202
Full Text | Full-Text PDF (38 KB)


EEG, hypometabolism, and ketosis during transcendental meditation indicate it does not increase epilepsy risk, 09 March 2005
Vernon A. Barnes
pages 202-203
Full Text | Full-Text PDF (37 KB)


The contribution of low plasma taurine to clinical complications of Homocystinurea, 29 March 2005
B. Mafrici
pages 203-204
Full Text | Full-Text PDF (41 KB)

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